The herbal drugs have a protective effect for kidney function against chemical toxicity. 24 male rats divided into 4 groups and treated as following, control group administrated orally with 1ml/kg. B.W physiological solution (0.9%), One dose Carbon Tetrachloride (CCl 4) 3 ml/kg. B.W, Silymarin 150 mg/kg. B.W and Silymarin150 mg/kg. B.W with CCl 3 ml/kg. B.W for 30 days. Oxidative stress resulted by CCl 4 caused increasing in Creatinine, Urea, total protein, Albumin, malondialdehyde (MDA) levels decreasing in Glutathione (GSH) and superoxide dismutase (SOD) levels in serum and congestion, degeneration and desquamation in kidney tissue. We concluded that Silymarin showed protective effect via increasing GSH, decreasing creatinine, Urea, total protein and MDA levels in serum and protect kidney tissue in rats.

This study was conducted to investigate if silymarin can prevent the adverse effect of oxidative stress induced by carbon tetrachloride(CCl4) on some characters of male rat reproductive system. Twenty male albino rats were divided into 4 groups, 5 for each included, control group, CCl4 group, silymarin group and silymarin plus CCl4 group. Groups with silymarin received dose (150mg/kg) and group with CCl4 received (3ml/kg) at the end of experiment. The period of the study was 35 days. CCl4 can induce male reproductive toxicity through damage testis structure, weights, reduction in epididymis, sperm count, morphology, viability and motility. Silymarin plays its antioxidant role with scavenging free radical resulted by CCl4 and showed significant increasing in body and testis weight, normal sperms counting and vital sperms in compared to CCl4 group.

The aim of this study is to compare the effects of Carnitine, Gensing, Dill and Arginine in characteristics of the sperms:total sperm, percentage of live and dead sperm, normal and abnormal sperm in male normal and exposuedrats to oxidative stress induced by hydrogen peroxide H2O2(0.5%) in drinking water during the experiment for 30 days. Fifty male rats used in age 12-14 weeks in weights (300-325g) divided randomly into 10 groups, included 5 in each group as following.  Control, H2O2 , Carnitine , carnitine + H2O2 , Gensing , Gensing + H2O2, Dill, Dill+ H2O2, Arginine, Arginine + H2O2 groups. Results showed: 1- Treating normal rats with Carnitine, Gensing , Dill, Arginine, led to a significant increase in value(P≤0.05) in Total sperm,  percentage of live sperm, and a significant decrease in dead sperm and no difference in normal and abnormal sperm  percentage  comparing to control group. 2- Oxidative stress Induced by H2O2 led to significant increase in value (P≤ 0.05) in percentage of abnormal sperm comparing to control group. While there were a significant decrease in value (P≤0.05) in Total sperm, percentage of live and normal sperm. 3- Treating rats exposure to oxidative stress with Carnitine, Gensing, Dill, Arginine, led to a significant decrease in value (P≤0.05) in percentage of abnormal and dead sperm, While the treating led to significant increase in Total sperm, percentage of live and normal sperm.

This study was conducted to investigate if silymarin can prevent the adverse effect of oxidative stress induced by carbon tetrachloride(CCl4) on some characters of male rat reproductive system. Twenty male albino rats were divided into 4 groups, 5 for each included, control group, CCl4 group, silymarin group and silymarin plus CCl4 group. Groups with silymarin  received dose (150mg/kg) and group with CCl4 received (3ml/kg) at the end of experiment. The period of the study was 35 days. CCl4 can induce male reproductive toxicity through damage testis structure, weights, reduction in epididymis, sperm count, morphology, viability and motility. Silymarin plays its antioxidant role with scavenging free radical resulted by CCl4 and showed significant increasing in body and testis weight, normal sperms counting and vital sperms in compared to CCl4 group.