Aim: The aim of this study was to evaluate the antimicrobial activity of Curcuma longa L. extract (CLE) on periodontal pathogens. Materials and Methods: Sixty patients were divided into three groups: Group I ( n = 20) patients treated with scaling and root planning (SRP) only, Group II ( n = 20) patients treated with SRP followed by subgingival irrigation with 1% CLE solution, and Group III ( n = 20) patients treated with SRP followed by subgingival irrigation with 0.2% chlorhexidine (CHX) solution. The clinical parameters (plaque index [PI], gingival index [GI] scores, probing pocket depths) were recorded at baseline, 4 weeks, and 8 weeks. The antimicrobial efficacy of 1% CLE and 0.2% CHX solutions against Porphyromonas gingivalis, Prevotella intermedia , and Aggregatibacter actinomycetemcomitans were evaluated by disk diffusion method. Results: There was no significant difference in the mean values of zone of inhibition exhibited by both CLE and CHX solutions. All the groups showed significant improvement in the clinical parameters when compared to baseline values. The improvement in the PI and GI scores in the CLE group was lesser than that in CHX group by the end of the study period. Conclusion: CLE possess antimicrobial efficacy against the common periodontopathic bacteria. However, further large-scale studies evaluating the substantivity of C. longa are required to support its beneficial use in the treatment of periodontal diseases.

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Aim: The present study aimed to assess the microleakage in primary teeth restored with tooth-colored materials using the dye penetration method. Materials and methods: A total of 60 healthy primary molar teeth were included in this study and standardized class II mesio-occlusal cavities were prepared on the samples. Consequently, these teeth were randomly divided into three experimental groups (n = 20 each group) such as group I: nano-filled resin-modified glass-ionomer, group II: nanocomposite resin, and group III: Cention N. After completing all the restorations, the restored teeth were subjected to 100 cycles of thermocycling. Next, all the surfaces of the tooth, except the restoration and a 1-mm zone adjacent to the restoration's margins, were covered with two coats of nail varnish. The coated teeth were then submerged in a 0.5% basic fuchsin dye solution. The teeth were then sectioned along the center of each restoration mesiodistally. Each part was visualized under a stereomicroscope at ×40 magnifications to assess microleakage. Results: Out of all the included restorative materials, the least microleakage was demonstrated by teeth restored by the nano-filled resin-modified glass-ionomer (RMGI) group (1.05 ± 0.21) followed by the Cention N group (1.84 ± 0.14) and the nanocomposite resin group (3.10 ± 0.03). A statistical method involving the analysis of variance revealed a statistically significant difference among the different restorative materials. Multiple comparisons among the restorative materials showed a statistically significant difference between groups I and II and groups II and III restorative materials (p < 0.05). The dye penetration score 1 was more [11(55%)] for the nano-filled RMGI group, score 3 was more [12(60%)] for the nanocomposite resin group, and score 2 was more [9(45%)] for the Cention N group. Conclusion:The present study showed significantly less microleakage associated with the nano-filled resin-modified glass ionomer group than nanocomposite resin and Cention N groups. Clinical significance: Since many years, dentists have encountered a challenging problem with cervical lesions. Thus, an interdisciplinary treatment approach is the appropriate option in the management of carious teeth that involve gingival recession and cervical extension.