Areca nut (Areca catechu Linn) is a plant that is widely distributed in tropical and subtropical regions. People have used it to treat various health problems. This study aims to determine the ability of betel nut ethanol extract to inhibit the growth of Staphylococcus aureus and Escherichia coli bacteria. The research method is experimental. Stages of research, first the betel nut is dried by aerating for 7-10 days. After drying, the seeds are ground into powder. The extraction stage of the active compounds uses the maceration method using 92% ethanol, evaporation is carried out using a rotary vacuum evaporator. The results of the maceration extract were carried out with phytochemical tests and bacterial inhibitory tests against E. coli, and S. aureus, carried out by the Kirby Bauer method. The detected metabolites were flavonoids, tannins and terpenoids. These metabolites have the ability as antimicrobials. The results of the inhibition test of the ethanol extract of areca nut seeds showed descriptively that the ethanol extract had a better inhibitory ability against S. aureus bacteria, compared to E. coli. The conclusion of this study is that the ethanol extract of areca nut seeds can inhibit the growth of E.coli and S.aureus.

Kualitas udara dalam ruangan (Indoor Air Quality) merupakan masalah yang perlu mendapat perhatian karena akan berpengaruh terhadap kesehatan manusia. Bakteri yang terdapat pada udara ruangan rumah sakit merupakan salah satu penyebab penyakit infeksi yang disebut infeksi nosokomial. Penelitian ini merupakan penelitian deskriptif dengan pendekatan observasional laboratorium untuk mengetahui kualitas bakteri udara di ruang operasi Rumah Sakit Abepura dan Rumah Sakit Dian Harapan di kota Jayapura. Penentuan jumlah sampel yang digunakan pada penelitian ini menggunakan metode total sampling, yaitu mengambil seluruh sampel ruang operasi di Rumah Sakit Umum Daerah (RSUD) Abepura dan Rumah Sakit Dian Harapan di Kota Jayapura. Setiap ruang diambil satu kali yaitu pada pagi hari dengan 2 titik pengambilan sampel. Tahapan penelitian ini di mulai dengan meletakan cawan petri yang berisi media PCA dan menghitung jumlah total angka kuman diruang operasi Rumah Sakit Abepura dan RS Dian Harapan. Hasil penelitian di RS Abepura indeks angka kuman pada ruang OK 1 sebesar 13 CFU/M³, OK2 sebesar 4 CFU/M³, OK 3 sebesar 1,3 CFU/M³ dan ruang OK 4 sebesar 0 CFU/M3. Hasil penelitian di RS Dian Harapan indeks angka kuman pada ruang OK 1 sebesar 4 CFU/M³, OK2 = 0 CFU/M3, OK 3 sebesar 6,5 CFU/M³ dan ruang OK 4 sebesar 11,7 CFU//M3. Kesimpulannya bahwa semua ruang operasi di RSUD Abepura dan RS Dian Harapan masih memenuhi syarat sesuai dengan baku mutu Permenkes no. 7 tahun 2019.

Pinang (Areca catechu L) secara tradisional dimanfaatkan untuk mengobati luka dan pendarahan, infeksi saluran kemih, sakit kaki dan kecacingan. Studi penelitian modern, pinang memiliki efek farmakologis sebagai antijamur. Penelitian ini bertujuan untuk mengetahui kemampuan ekstrak etanol biji pinang terhadap pertumbuhan jamur Candida albicans. Penelitian ini merupakan penelitian eksperimen. Langkah-langkah yang dilakukan dalam penelitian ini, mula-mula biji pinang yang telah dikupas dijemur selama 7-10 hari. Setelah kering, dihaluskan menjadi serbuk. Selanjutnya proses ekstraksi fitokimia menggunakan metode maserasi menggunakan etanol. Perolehan ekstrak dilakukan menggunakan rotary vacuum evaporator. Ekstrak yang diperoleh dibuat taraf konsentrasi 20, 40, 60 dan 80 g/ml. Masing-masing taraf konsentrasi dilakukan uji daya hambat anti jamur menggunakan metode Kirby Bauer. Zona bening yang terbentuk diukur menggunakan jangka sorong. Data dianalisis menggunakan statistik non Parametrik Kruskal Wallis dan uji lanjut Mann-Whitney U. Secara deskriptif daya hambat ekstrak etanol biji pinang memiliki kemampuan daya hambat terhadap jamur C. albicans. Analisis statistik semua taraf konsentrasi memberikan pengaruh yang nyata dalam menghambat pertumbuhan jamur. Uji lanjut menunjukkan konsentrasi 20 g/ml dan 80 g/ml serta 60 g/ml dan 80 g/ml memiliki nilai signifikasinya <0,05, yang berarti ada perbedaan pengaruh dalam menghambat pertumbuhan jamur C. albicans. Kesimpulan penelitian ini adalah ekstrak etanol biji pinang dapat menghambat pertumbuhan jamur C. albicans.

Covid-19 is a disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus. data as of July 27, Covid 19 sufferers in Papua reached 2130 cases. The research objective was to determine the pattern of the spread of Covid 19 infection in Papua Province in 2020. The descriptive research method was cross-sectional design, using secondary data obtained from the Covid 19 Task Force Team of the Papua Provincial Health Office. The results showed the increase in May as many as 533 cases. The highest number of people with Covid-19 based on age is 20-60 years old. Based on sex, the highest percentage is male, this is due to the natural immune response and the immune response acquired during viral infection between women and men. Based on the evidence that shows that Covid 19 infection attacks many non-Papuan tribes compared to Papuans. The incidence of Covid 19 cases of ethnicity related to socio-economic, cultural, genetic factors, vulnerability to susceptibility or response to infection. The number of cases recovered against Covid 19 for the period March 22 to July 22 2020 the number of cases was 1956, while the number of cases died was 23 people. The cure rate is the result of many factors, which indicate the patient's physiological ability to attack Coronavirus. Conclusion; The highest number of males in May was 533 people, the age range of sufferers was 20 - 60 years, more men than women, less ethnic Papuans than non-Papuan ethnics, 27 July the number of people who recovered in 1956 while 23 people died.

Mosquito vectors are a severe threat to the prevalence and incidence of malaria, dengue fever, yellow fever, and filariasis. Malaria is a Plasmodium infection that is transmitted by the female Anopheles mosquito. Malaria cases in tropical and subtropical countries have social and economic impacts. Mosquito vector control has been using chemical and synthetic compounds. This method can reduce malaria cases, but it creates new problems that also slow down the elimination of malaria in the long run. Vector control in the larval phase using bioactive compounds of various plants is an alternative to eradicating vectors; besides that, utilizing these bioactive compounds is relatively safer, cheaper, and more accessible. Plants contain several compounds that are toxic to Anopheles mosquito larvae. This literature study summarizes research on extracts of various plants that function as larvicides of the Anopheles mosquito. The research method uses a literature study. The literature related to the research topic was obtained from the databases of Google Scholar, Semantic Sholar, Garuda, PubMed, and Science Direct. The primary literature is a publication of the last ten years. The literature study results showed that the plants Vitex negundo Linn., Lawsonia inermis Linn., Stachys byzantina K.Koch., Pithecellobium dulce Bth., Olax dissiti?ora Oliv., Ipomea cairica Linn., Ricinnus communis Linn., Carica papaya Linn., Paederia foetida Linn., Glycosmis pentaphylla Retz., Terminalia chebula Retz., Annona squamosa Linn., Tagetes erecta Linn. and Azadiracha indica Juss. against mosquito vectors. This study concludes that secondary plant metabolites can be used as candidates and alternatives for controlling Anopheles mosquito larvae.