One PFOS alternative, ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy) propanoate, known as GenX, was created to replace one of the original PFAS. This small and tough molecule has been found in surface water, groundwater, drinking water, rainwater, and air emissions in some areas in the United States. Recently, GenX has been shown to have an impact on several disease-related proteins in humans, and just like PFOS, it binds to human protein human serum albumin (HSA). In this paper, we reported four binding sites of GenX on HSA protein via docking and molecular dynamics simulation.
Enhancing the production rate while maintaining control in electrospinning has been a challenge for years. This work proposes a novel spinneret from a tube with a single wire loop embedded in its one end. With the feeding of solution precisely controlled and the spinning process stablized, multiple polymer jets can be continuously generated from the wire loop. The as‐spun fibers show nanofibrous structure and its fiber diameter is greatly affected by the applied voltage and polymer concentration. As compared to needle electrospinning, the wire loop spinneret generates a stronger electric field with a larger spinnable area due to its special geometrical structure and a higher applied voltage it is connected to. Slightly coarser nanofibers are fabricated as compared to the nanofibers from needle electrospinning and the production rate is as high as 0.48 g h−1.
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