Bacteriological characteristics of abattoir effluents (wastewater), abattoir water source, and water bodies receiving abattoir wastewater were investigated in Abuja, Nigeria using the multiple-tube fermentation technique. Source of water to the abattoirs and the usage of water bodies receiving abattoir effluents were determined using questionnaires. Bacterial counts ranged from 4.8 × 106 to 5.8 × 105 /100 mL of total coliform (TC), 8.2 × 104 to 3.2 × 104/100 mL of Fecal coliform (FC), 5.2 × 104 to 2.0 × 104/100 mL of Fecal streptococcus and 1.2 × 104 to 2.0 × 103/100 mL of Escherichia coli for abattoir effluents 6.6 × 105 to 6.0 × 105/100 mL of TC, 6.2 × 104 to 1.8 × 104/100 mL of FC, 1.8 × 104 to 6.0 × 103/100 mL of F. streptococcus, and 4.8 × 103 to 6.6 × 102/100 mL of E. coli for water bodies receiving abattoir effluents 100 m downstream. TC bacteria counts for abattoir effluents exceeded recommended limit for discharge into surface water in Nigeria. No significant difference (P < 0.05) was observed between bacterial counts of abattoir effluents and receiving water bodies 100 m downstream: an indication of contamination of receiving water bodies by abattoir effluents and possible public and environmental health hazards.

Sensory information arising from the airways is processed in a distributed brain network that encodes for the discriminative and affective components of the resultant sensations. These higher brain networks in turn regulate descending motor control circuits that can both promote or suppress behavioural responses. Here we explore the existence of possible descending neural control pathways that regulate airway afferent processing in the brainstem, analogous to the endogenous descending analgesia system described for noxious somatosensation processing and placebo analgesia. A key component of this circuitry is the midbrain periaqueductal grey, a region of the brainstem recently highlighted for its altered activity in patients with chronic cough. Understanding the nature and plasticity of descending neural control may help identify novel central therapeutic targets to alleviate the neuronal hypersensitivity underpinning many symptoms of respiratory disease.

Augmented breaths, also known as sighs, constitute the normal repertoire of breathing in freely behaving humans and animals. The breaths are believed to be generated by neurones in the preBötzinger complex but under modulatory influence from higher brain centres, particularly in the limbic system due to the strong correlations between the expression of emotional behaviours such as anxiety and the occurrence of augmented breaths. The current study examines the role of the hippocampus in the motor expression of augmented breaths, and also examines the characteristics of eupneic breaths surrounding a sigh before and after stimulating the hippocampus in urethane anaesthetised Sprague-Dawley rats. Neurochemical microstimulation using the excitatory amino acid, D,L-Homocysteic acid, was used to locate areas in the hippocampus with the potential to modulated the motor expression of augmented breaths. The CA1 neurone cluster of the ventral hippocampus was found to completely suppress the expression of augmented breaths without affecting the intrinsic properties of the breaths. A similar neurone cluster, but in the dorsal field of the hippocampus, was also investigated and found to have no effects over the expression of augmented breaths. The data supports the hypothesis that there is a structural or functional relationship between neurones of the ventral hippocampus and brainstem nuclei that control augmented breaths. The implications of these findings in the context of behaviours are discussed but with due consideration of experimental conditions.

Anatomy of the mystacial vibrissae in the African giant pouched rat was investigated to establish the role played by these structures in the adaptation of the rodent to its subterranean environment. Gross morphology was based on direct observation of the mystacial vibrissae with the naked eyes, while histology was based on light microscopic examination of the same structure stained with haematoxylin and eosin (H/E), Masson's trichrome (MT) and Masson-Fontana reducing method for melanin. The mystacial vibrissae were aligned in 5-6 rows on each side of the face. The length increased rostrocaudally in each row. The mean number of vibrissae was 55.29 (± 3.42). The vibrissal folliclesinus complex extended into the reticular layer of the dermis. In the proximal part of the sinus, trabeculae of connective tissues connected the internal and external dermal sheaths. The most distal part of the sinus contained blood vessels. The external dermal sheaths were thick and held in position by muscle fibres. Mean thickness of the cortex and medulla in the complex were 1.626 µm (± 0.110) and 0.775 µm (± 0.057), respectively. The thick external dermal sheaths were laden with mechanoreceptors. The thick cortex provided the needed elasticity necessary for touch and sensation. In conclusion, the well developed mystacial vibrissa in the African giant pouched rat is an important compensation for poor vision, necessary for an effective adaptation.

A 9-month old male Boerboel was presented at the University of Abuja Small Animal Clinic with a primary complaint of inappetence and micturition with brownish-yellow urine. Physical examination revealed pale mucous membranes, enlarged pre-scapular lymph nodes, bilateral ocular discharges, pyrexia (41.2 °C), depression and the presence of ticks of the genus Rhipicephalus sanguineus on the body of the animal. History revealed that the dog was recently vaccinated against canine distemper, hepatitis, leptospirosis, parainfluenza, parvovirus (DHLPP) and rabies six days prior to the onset of clinical signs, and had been anorexic. Following clinical examination, blood and faecal samples were collected for biochemical and parasitological analyses, and the results revealed the presence of intraerythrocytic Babesia parasites, normocytic and normochromic anaemia with extensive cellular damage. However, during the course of the investigation, the dog died. With appropriate consent, a post-mortem examination was carried out. Diffuse oedema with interstitial pneumonia in the lung, focal haemorrhage with cellular infiltration in the heart and progressive necrosis of epithelial cells within the seminiferous tubules of the testicles were observed. Many of the observed clinicopathological alterations were consistent with complicated babesiosis. However, in the current case, some unique systemic complications such as testicular degeneration, which has not been previously observed in the Boerboel are discussed.