Introduction In Russia, the prevalence of GERD is 18-46% [Ivashkin V. T., Maev I. V., Trukhmanov A. S., 2011]. GERD leads to a significant decrease in the quality of life of patients, especially with nocturnal symptoms, extraesophageal symptoms (chest pain, persistent cough), and increases the risk of complications such as bleeding from ulcers and erosions, peptic strictures and, which causes the greatest caution, Barrett’s esophagus and esophageal adenocarcinomasObjectivesThe medical and social significance of the pathology of the thyroid gland and gastrointestinal tract problem is determined by their high prevalence regardless of age, the annual increase in morbidity and the decrease in the quality of life (QOL).MethodsPatients were divided in two groups: patients with GERD; patients with GERD and hypothyroidism. Quality of life was studied using the non-specific (general) SF 36 questionnaire.ResultsThe lowest indicators were shown by patients with GERD and hypothyroidism (PF scale - Me 75.00 and 45.00 (p=0.005470), RF scale - 75,00 and 25.00 (p=0.043046), BP scale - 74.00 and 52.00 (p=0.036493), GH scale - 58.00 and 15.00 (p=0.009959)). The second group was more disadvantaged (VT scale - IU 52.50 and 32.50 (p=0.098125), SF scale - 75 00 and 50.00 (p=0.019016), RE scale - 33.30 and 0.00 (p=0.028841), GH scale - 48.00 and 36.00 (p=0.025919).ConclusionsAccording to the results, the presence of combined pathology of the thyroid gland and gastrointestinal tract significantly affected the physical and psychological component of health in the studied patients.

The aim of this work is to assess the prevalence and risk factors of depression in patients with gastroesophageal reflux disease (GERD) and patients with GERD and hypothyroidism. The survey was conducted in 124 adult patients. The Beck and Spielberger-Khanin scales were used to diagnose depression and anxiety. The prevalence of current depression was 29.4 % in patients with GERD and 60.0 % in patients with GERD and hypothyroidism. In the group of patients with GERD, personal anxiety is more pronounced, whereas in the group of patients with GERD and hypothyroidism, personal anxiety is less pronounced than situational anxiety.

The aim of the work is to compare the characteristics of quality of life and comorbid mental disorders in patients in the group with isolated gastroesophageal reflux disease (GERD) and in patients with combined pathology (GERD in combination with hypothyroidism) using the symptomatic questionnaire by Yu. Aleksandrovich and SF 36 questionnaire. The survey was conducted in 124 patients aged 18 to 65 years. Anxiety disorders are the most common among the mental disorders in patients with GERD, while depressive and psychasthenic disorders prevail in patients with combined pathology. All indicators of quality of life were lower in the patients with combined pathology.