Abstract. A method for the consistent production of epithelial‐lined cysts in the mandibles of rats is described. Attached gingiva from the interdental papilla was excised and implanted into prepared cavities in the mandible. The animals were examined at time periods varying from 0 to 45 days later. Twenty‐seven of the 28 animals examined after 7 days or longer had developed cysts. An interpretation of the pathogenesis of these cysts was made based on histologic observations and measurements of the cysts at the various time intervals.

Abstract. Rats were passively immunized by an intraperitoneal injection of homologous anti‐BSA serum and their salivary glands were challenged 20 min or 24 hours later with BSA by the intraductal route. Immune complex sialoadenitis developed only when challenge was early. It is concluded that immunoglobulins are transferred from the circulation into the salivary glands and are relatively rapidly cleared by a mechanism yet unknown, possibly by salivary flow.

Antiserum to ammonium sulphate-soluble proteins of rat saliva was raised in rabbits. The introduction of this antiserum, via the excretory duct, into the parotid gland of rats induced severe acute sialoadentis. It is suggested that the inflammatory response developed as a result of formation of immune complexes, composed of acinar epithelial antigens and the antibodies introduced from without.