Twenty-four cases of Intravascular Papillary Endothelial Hyperplasia (IPEH) have been studied. IPEH comprises approximately 2% of benign and malignant vascular tumours of the skin and subcutaneous tissue. This peculiar tumour-like process lacks specific clinical characteristics and its diagnosis must be based on microscopic examination. Histologically is is characterised by a papillary proliferation of endothelial cells forming vascular channels, commonly associated with thrombus and in some cases simulating angiosarcoma.--Follow-up of 10 cases indicates a benign clinical course.
The well-defined circumscription and the presence of mesothelial component intermingled with the leiomyomatous proliferation favors the hypothesis that a leiomyo-adenomatoid tumor should be considered as a subtype of adenomatoid tumor with distinctive morphological features. Only four previous cases of this rare neoplasm have been reported to date, one in the epydidimis and the other three cases in the uterine wall, one of them affecting also to the right ovary.
Flagellate erythema, described by Moulin in 1970 as reminiscent of the lesions produced by flogging and by other authors as zebra-like lesions, was noted first in association with bleomycin treatment, but later occasionally reported in relationship with dermatomyositis, mostly from Japan. It is characterized by linear, erythematous, cutaneous streaks, pruriginous or painful, arising on an oedematous background and disappearing spontaneously over several weeks. So far, fewer than five cases have been reported in association with dermatomyositis, but we now present a further one.
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