Evaluation of the direct registration of brain cortical and hippocampal activity during a high-frequency electromagnetic field (HF-EMF) exposure was performed. Experimental procedures were done under general anesthesia (urethane, 20%, 2g/kg i.p.) in Lurcher mutant mice, wild type (healthy littermates) were used as controls. Animals were exposed to the HF-EMF with frequency corresponding to cellular phones (900 MHz). We used of gel electrodes (silicon tubes or glass microcapillary filled with agar) where the connection with classical electrodes was located out of HF-EMF space. ECoG evaluation showed a distinct shift to lower frequency components but clear effect has been observed only in wild type (healthy) mice whereas in Lurcher mutant mice only gentle differences between frequency spectra were found. Measurement of hippocampal rhythmicity showed gentle changes with increase of higher frequencies (i.e. opposite effect than in cortex) and changes in theta oscillations registered from a dentate gyrus and CA1 area in both types of animals (healthy and mutant). These findings support an idea about possible influencing the central nervous system by HF-EMF exposure and support also some recent results about possible health risks resulting from cellular phones use.
The whole-body exposure system for unrestrained mice was designed in order to analyze the influence of electromagnetic field. The setup operating at 900MHz was designed with respect to induced uniform field, external radiation elimination, absorbed power determination, sufficient space for mice movement together with even mice exposure and costs. The main aim of this paper is to assure that the dosimetry results reached by computer simulations can be used for determination of absorbed power in the unrestrained mouse. The wholebody exposure chamber with anatomical mouse model was simulated by two different numerical methods: finitedifference-time-domain method (FDTD) and Finite Integration Technique (FIT) and its dosimetry results were compared by computed SAR values. In our contribution we will describe our first results dealing with observed biological effects of EM field, obtained by real exposures of experimental animals.
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