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Acute normovolaemlc haemodilution does not reduce the inflammatory process induced by facial surgery The place of preoperative acute normovolaemic haemodilution (haematocrit = 28%-32%) in reducing postoperative inflammation was evaluated after facial surgery. Thirty-two patients scheduled for mandibular osteotomy were randomized to a nonhaemodiluted group or to a haemodiluted group. The degree of postoperative inflammation was evaluated:-first by an xray technique (radiotelemetry) providing measurements of the tissue thickness (quantitation of facial oedema), and second by the measurement of four acute phase protein plasma concentrations during the.first postoperative week. Throughout the study, no changes in facial oedema or in variation of acute phase proteins were detected after haemodilution. It is concluded that acute normovolaemic haemodilution has no effect on the intensity of facial oedema and the biological inflammation process after facial surgery. Le but de cette dtude prospective est d~valuer l'effet de lh~modilution pr~op~ratoire (h~matocrite = 28% gt 32%) sur la r~action inflammatoire aprbs chirurgie faciale. Trente-deux patients devant b~n~ficier d'une ost~otomie mandibulaire ont ~t~ ~tudi~s. Aprbs randomisation, 16 ont ~t~ h~modilu~s et 16 autres non-h~modilu~s. L'ampleur de la rdaction inflammatoire postop~ratoire a ~t~ ~valu~e gJ l'aide de deux techniques. D'une part, par tdldradiomdtrie, technique radiographique qui permet la mesure de l~paisseur des tissus mous et donc l~valuation de la r~action oed~mateuse postop~ratoire. D'autre part, par le dosage plasmatique r~p~t~ de diff~rentes prot~ines de Finflammation durant la premiere semaine postop~ratoire. Les

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