Three questionnaire studies investigated Spanish and English readers' interpretations of sentences with complex noun phrases (NPs) such as "I really liked the preface of the book that I read yesterday." These complex NPs are ambiguous between two readings, one in which the relative clause (RC) that I read yesterday modifies the first noun, N1, preface, or the second noun, N2, book. Cuetos and Mitchell (Cognition, 1988, 30, 73-105) claimed that Spanish was biased toward having the RC modify N1, which they claimed was evidence against the cross-language universality of the late closure parsing principle. We demonstrate that the preference for N1 versus N2 modification varies greatly between different construction types within both Spanish and English while the variation between languages is relatively minor, but still of interest. The effect cannot be reduced to an effect of plausibility, but seems to reflect directly certain syntactic and semantic aspects of the constructions studied. We claim that relative clauses and other "nonprimary" phrases are not parsed following such parsing principles as late closure, but instead follow principles we advance in the form of the construal hypothesis. Thus, it is not the case that late closure is a language-specific strategy; rather, it and similar structural parsing principles are specific to only certain classes of phrases within a language.

An experimental study on two decision issues for wrapper feature selection (FS) with multilayer perceptrons and the sequential backward selection (SBS) procedure is presented. The decision issues studied are the stopping criterion and the network retraining before computing the saliency. Experimental results indicate that the increase in the computational cost associated with retraining the network with every feature temporarily removed before computing the saliency is rewarded with a significant performance improvement. Despite being quite intuitive, this idea has been hardly used in practice. A somehow nonintuitive conclusion can be drawn by looking at the stopping criterion, suggesting that forcing overtraining may be as useful as early stopping. A significant improvement in the overall results with respect to learning with the whole set of variables is observed.

PURPOSE:To present fundamental anatomical aspects and technical skills necessary to urethra and urinary bladder catheterization in female mice and rats. METHODS: Urethral and bladder catheterization has been widely utilized for carcinogenesis and cancer research and still remains very useful in several applications: from toxicological purposes as well as inflammatory and infectious conditions to functional aspects as bladder dynamics and vesicoureteral reflux, among many others. RESULTS: Animal models are in the center of translational research and those involving rodents are the most important nowadays due to several advantages including human reproducibility, easy handling and low cost. CONCLUSIONS: Although technical and anatomical pearls for rodent urethral and bladder access are presented as tackles to the advancement of lower urinary tract preclinical investigation in a broaden sight, restriction to female animals hampers the male microenvironment, demanding future advances. Key words: Urinary Tract. Rodent Diseases. Anatomy. Rats. RESUMO OBJETIVO:Apresentar aspectos anatômicos fundamentais e habilidades técnicas necessárias para cateterismo da uretra e bexiga em ratos e camundongos fêmeas. MÉTODOS: Cateterismo vesical tem sido amplamente utilizado na pesquisa do câncer e carcinogênese, além de várias outras aplicações, desde fins toxicológicos, condições inflamatórias e infecciosas até aspectos funcionais como a dinâmica vesical e refluxo vesico-ureteral, entre muitos outros. RESULTADOS: Os modelos animais estão no centro da investigação de translação e os roedores são os mais importantes devido a várias vantagens, incluindo reprodutibilidade humana, o fácil manuseio e baixo custo. CONCLUSÕES: Apesar de permitir o desenvolvimento da investigação pré-clínica do trato urinário inferior, o modelo se restringe aos animais do sexo feminino, de modo que avanços futuros são necessários. Descritores: Sistema Urinário. Doenças dos Roedores. Anatomia. Ratos. Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool

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