The voltammetric behavior of pyrimethamine (PMT) was studied by square-wave (SW) and square-wave stripping (SWS) techniques, leading to two methods for its determination [in presence of sulfaquinoxaline (SQX)] in aqueous samples and veterinary formulations. Due to overlapping response of SQX and PMT the first derivative was used for the simultaneous determination of these two components. The relative standard deviations obtained for concentration levels of PMT as low as 3 x M (SW) and 5 x lo-' M (SWS) were 2.2% and 2.7% (n = lo), respectively.
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