The khmer package is a freely available software library for working efficiently with fixed length DNA words, or k-mers. khmer provides implementations of a probabilistic k-mer counting data structure, a compressible De Bruijn graph representation, De Bruijn graph partitioning, and digital normalization. khmer is implemented in C++ and Python, and is freely available under the BSD license at
https://github.com/dib-lab/khmer/.
Hydrothermal reaction of metal oxalate
(ox) salts and bis(4-pyridylmethyl)piperazine
(bpmp) afforded a series of coordination polymers that were structurally
characterized by single-crystal X-ray diffraction. {[Cd(H2O)4(bpmp)](ox)}
n
(1) and {[Co(H2O)4(bpmp)](ox)}
n
(2) show isostructural cationic one-dimensional
(1D) coordination polymer chain motifs with unligated ox anions. A
higher temperature polymorph of 2, {[Co(ox)(bpmp)]·3H2O}
n
(3), possesses
a system of threefold interpenetrated three-dimensional (3D) diamondoid
nets. {[Mn(H2O)4(bpmp)] [Mn2(ox)3]·5H2O}
n
(4) manifests a unique 1D + 2D → 3D polyrotaxane coordination
polymer structure with 1D cationic [Mn(H2O)4(bpmp)]
n
chains threaded through apertures
coursing through parallel stacks of anionic [Mn2(ox)3]
n
two-dimensional (2D) hexagonal
layers. {[Cu2(ox)2(bpmp)]·6H2O}
n
(5) possesses 2D [Cu2(ox)2]
n
layers pillared
by bpmp ligands into a 3D [Cu2(ox)2(bpmp)]
n
coordination polymer network with an unprecedented
4,4-connected self-penetrated (5383)2(5482) topology. Variable temperature magnetic
susceptibility studies showed weak antiferromagnetic coupling along
[Co(ox)]
n
chain submotifs in 3 with concomitant zero-field splitting (J = −4.1(7)
cm–1, D = 34.5(6) cm–1), weak antiferromagnetic coupling within the [Mn2(ox)3]
n
hexagonal layers in 4 (J ∼ −0.5 cm–1),
and strong antiferromagnetic coupling within the 2D [Cu2(ox)2]
n
layers in 5 (J = −220(6) cm–1).
This paper presents the first draft genome of the tule elk (
Cervus elaphus nannodes), a subspecies native to California that underwent an extreme genetic bottleneck in the late 1800s. The genome was generated from Illumina HiSeq 3000 whole genome sequencing of four individuals, resulting in the assembly of 2.395 billion base pairs (Gbp) over 602,862 contigs over 500 bp and N50 = 6,885 bp. This genome provides a resource to facilitate future genomic research on elk and other cervids.
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