High-frequency array transducers can provide higher imaging resolution than traditional transducers, thus resolving smaller features and producing finer images. Commercially available ultrasonic transducers are mostly made with lead-based piezoelectric materials, which are harmful to the environment and public health. This paper presents the development of the 64-elements high-frequency (18.3 MHz) lead-free linear array ultrasonic transducer based on (KNaLi)(NbTaSb)O (KNLNTS) piezoceramic. Array elements were spaced at a 75- pitch, and interconnected via a custom flexible circuit. The two matching layers and a light backing material were used to improve the performance of the array. The developed KNLNTS ceramic-based lead-free linear array exhibited a center frequency of 18.3 MHz, an average -6-dB bandwidth of 42%, an average two-way insertion loss of 41.8 dB, and a crosstalk between the adjacent elements of less than -53 dB near the center frequency. An image of a tungsten wire phantom was acquired using a Verasonics Vantage research ultrasound system. Results from imaging tests demonstrated a good imaging capability with a spatial resolution of axially and laterally, indicating that the lead-free linear array ultrasonic transducer based on KNLNTS ceramics is a promising alternative to lead-based transducers for ultrasound medical imaging.

Objective Coronary slow flow (CSF) is characterized by delayed opacification of distal epicardial coronary arteries without significant coronary stenosis. In addition, The changes of lipoprotein-associated phospholipase A2 (Lp-PLA2) as a significant predictive factor for CSF remain controversial. The study aims to investigate the association between plasma Lp-PLA2 and CSF. Methods In this retrospective study, 170 consecutive patients who underwent coronary angiography were enrolled in Beijing Anzhen Hospital from January 2017 to September 2019, and were divided into CSF group and normal control groups. According to coronary blood flow rate measured by the thrombolysis in myocardial infarction frame count (TFC) method, CSF was defined as TFC > 27. Serum Lp-PLA2 levels were measured in an enzyme-linked immunosorbent assay. Results Lp-PLA2 levels were higher in the CSF group than in the control group (288.6 ± 50.3 versus 141.9 ± 49.7, P < 0.001) and were significantly correlated with the mean coronary artery thrombolysis in myocardial infarction (TIMI) frame count (r = 0.790, P<0.001). Logistic regression analysis showed that high Lp-PLA2 was independently associated with CSF after adjustment for conventional risk factors (OR = 1.040, CI = 1.022–1.059, P<0.001). Male sex (OR = 2.192, CI = 1.161–4.140, P = 0.016) and hypertension (OR = 1.965, CI = 1.034–3.736, P = 0.039) were also CSF risk factors. Receiver-operating characteristic curve (ROC) analysis showed that Lp-PLA2 levels can predict CSF severity; the predictive power was higher than the other risk factors. Conclusion Our study demonstrated that patients with CSF had higher circulating levels of Lp-PLA2 than normal controls. After adjustment for potential confounders, increased Lp-PLA2 was independently associated with presence of CSF.

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As a new high-end bearing product, full ceramic ball bearings are favoured in a variety. However, there have been few studies on the lubrication of full ceramic ball bearings. The purpose of this study is to reveal the relationship between the vibration and temperature rise of full ceramic angular contact ball bearings and the lubricant viscosity, and to improve the service life of the bearings. In this study, the effects of lubricant viscosity on the vibration and temperature rise of silicon nitride full ceramic angular contact ball bearings under different axial loads and rotation speeds were tested. Herein, a mathematical model of oil lubrication suitable for full ceramic ball bearings is established and the relationship between the lubricant viscosity, lubricant film thickness, outer ring vibration and temperature rise of the bearing is analyzed. It was found that the vibration and temperature rise first decrease and then increase with the increase of lubricant viscosity. In this range, there is an optimal viscosity value to minimize the vibration and temperature rise of the full ceramic angular contact ball bearing. The contact surface wear of the full ceramic angular contact ball bearing varies greatly under different lubricant viscosities. There is no obvious wear on the contact surface under optimal viscosity, and the service life of the bearing is greatly improved. These results can play an important role in revealing the lubricant mechanism of full ceramic ball bearings and improving their service life under optimal lubrication.