The book consists of nine chapters explaining the concept of Good to Great. Starting from emphasizing that “good is the enemy of great”, Jim Collins provides great explanations as well as arguments of why his concept is very important for leaders who want to be successful in their efforts of building “enduring results” of their companies, organizations, or institutions. He in detail explains four principles underlining the framework of good to great. There are disciplined people (level 5 leadership and first who, then what concepts), disciplined thought (confront the brutal facts and the Hedgehog concepts), disciplined action (culture of discipline and the flywheel concepts), and building greatness to last (clock building, not the time telling and preserve the core/stimulate progress concepts). For further analysis of the Good to Great, I will shortly summarize the concept of how to make something good to be great explained in the book in the following section. I will also conclude this paper by commenting on the concept as my critique toward the theory of Good to Great.
ObjectiveThe objective of this study was to compare the periodontopathogen prevalence and tetracycline resistance genes in Dominican patients with different periodontal conditions.MethodsSeventy-seven samples were collected from healthy, gingivitis, chronic (CP) and aggressive (AgP) periodontitis patients. Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Prevotella intermedia, Parvimonas micra, Eikenella corrodens and Dialister pneumosintes and 11 resistance genes were studied by PCR. P. gingivalis fimA genotype was determined.ResultsIn healthy patients, P. micra and P. intermedia were the most and least frequently detected, respectively. T. forsythia and E. corrodens appeared in 100 % of gingivitis patients. Red complex, D. pneumosintes and E. corrodens were significantly more prevalent in CP compared to healthy patients. F. nucleatum and T. denticola were detected more frequently in AgP. A. actinomycetemcomitans was the most rarely observed in all groups. The fimA II genotype was the most prevalent in periodontitis patients. Seven tetracycline-resistant genes were detected. tet(Q), tet(32) and tet(W) showed the greatest prevalence. tet(32) was significantly more prevalent in CP than in healthy patients.ConclusionsRed complex bacteria and D. pneumosintes were significantly the most prevalent species among periodontitis patients. T. forsythia was the most frequently detected in this population. To our knowledge, this is the first study describing the tet(32) gene in subgingival biofilm from healthy and periodontally diseased subjects.Clinical relevanceThis study contributes to the knowledge on the subgingival microbiota and its resistance genes of a scarcely studied world region. Knowing the prevalence of resistance genes could impact on their clinical prescription and could raise awareness to the appropriate use of antibiotics.Electronic supplementary materialThe online version of this article (doi:10.1007/s00784-015-1516-2) contains supplementary material, which is available to authorized users.
We conclude that clinical attachment loss is common in adolescents in Santo Domingo, Dominican Republic, suggesting the necessity for improved standards of prevention, diagnosis, and treatment of these lesions.
Vdues B Y J I M C O L L I N Sxecutives spend too much time drafting, wordsmithing, and redrafting vision statements, mission statements, values statements, purpose statements, aspira-
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