Amidoximes are an interesting class of compounds. They can serve as starting materials for the synthesis of valuable heterocyclic and other useful compounds. Their use as starting materials has enabled a wide range of applications in novel pharmaceuticals, antitumor agents, antimalarial agents, nitric oxide synthase (NOS) substrates, enhanced textile materials, synthetic polymers and chelating resins. Concerning the chemistry of amidoximes, during the last 22 years some new methodologies as well as improvements of previously reported reactions appeared in the literature. In this review is discussed the application and methods used for synthesis of amidoximes.

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Resumo A síntese do 6-acetil 1,2:3,4-di-O-isopropilideno-α-D-galactopiranose a partir da reação de acetilação do 1,2:3,4-di-O-isopropilideno-α-D-galactopiranose utilizando a argila montmorilonita K10 como promotor é descrita. O protocolo é rápido, eficiente, econômico, livre de solvente e quimiosseletivo. O produto foi obtido em excelente rendimento (95%), curto tempo reacional (7,5 min), em temperatura ambiente e sem a necessidade de purificação adicional. Adicionalmente, essa argila manteve sua atividade catalítica por três ciclos reacionais sem diminuição de eficiência.

The synthesis of C-glycosides, sugar analogs in which glycosidic oxygen is substituted by a carbon atom, is of particular interest due to their usefulness as key intermediates for assembling biologically active molecules and natural products. Despite their challenging chemistry, due to their versatility, C-glycosides play a pivotal role in the development of the chemistry of novel materials and bioactive molecules. In this review, we present of various synthetic methodologies, mechanistic proposal and application for 2,3-unsaturated C-glycosides in the last twenty years.

Carbohydrates are the most abundant biomolecules on Earth and annually approximately 200 billion tons of these compounds are produced by the higher plants and algae. Among the many compounds classified as carbohydrates, D-glucose is by far the most abundant monosaccharide. Dglucose is one of the few carbohydrates of low molecular mass, economically attractive, produced on a large scale and prone to structural modifications for the production of new compounds. Dglucose is used in the most varied industrial sectors, such as: in food, pharmaceutical, cosmetic, chemical, among others. Therefore, the annual increase in demand for D-glucose is justifiable, in which it can be obtained by different industrial processes, such as acid hydrolysis and enzymatic hydrolysis. Due to the relevance of D-glucose, this article presents a review on the history, properties, production and biosynthesis of this compound.