No abstract

Permanent work disability administered through social security was encountered in 5.3% of the Crohn's patients followed in our cohort. Patients who consistently report low quality of life, or have frequent flares requiring surgical intervention or hospitalization for medical management, may be at risk for CD-related work disability.

Budesonide may be a safe option for treatment of CD during pregnancy.

SUMMARYBackground: Ribavirin is associated with haemolytic anaemia. Antioxidants have been reported to decrease severity of this anaemia. Aim: To determine effect of vitamin E supplementation on ribavirin-associated haemolysis in chronic hepatitis C treated with standard a-interferon and ribavirin. Methods: Fifty-one naive chronic hepatitis C patients were randomized to receive either a-interferon/ribavirin therapy (control) or therapy plus vitamin E 800 IU b.d. with 24-week follow-up. Alanine aminotransferase ALT, haemoglobin and reticulocyte percentage were monitored. Symptoms and health-related quality of life were also monitored at each visit. Results: Forty-seven subjects were treated (27 vitamin E /20 controls). Thirteen withdrew because of adverse

No abstract