Bone marrow infiltration (BMI), categorized as an extra-nodal site, affects stage and is associated with poor prognosis in newly diagnosed lymphoma patients. We have evaluated the accuracy of PET/CT and bone marrow biopsy (BMB) to assess BMI in 372 lymphoma patients [140 Hodgkin Lymphoma (HL) and 232 High Grade B-cell non-Hodgkin Lymphoma (HG B-NHL), among them 155 Diffuse Large B-Cell Lymphoma (DLCL)]. For HL cases, and taking into account PET/CT, sensitivity, negative predictive value (NPV) and accuracy were 96.7, 99.3, and 99.3% while those of BMB were 32.3, 83.8, and 85%, respectively. For HG B-NHL and considering PET/CT, sensitivity, NPV, and accuracy were 52.7, 81.7, and 84.1%, while those of BMB were 77.6, 90.2, and 90.7%, respectively. In the HG B-NHL group, 25 patients would have been under-staged without BMB. These results lead us to recommend PET/CT and the avoidance of BMB to assess BMI in HL. In the case of HG B-NHL, bone marrow status should be assessed firstly by means of PET/CT; only in either focal or diffuse PET/CT with low borderline SUV max values or in negative cases, should BMB be carried out afterwards. In the HG B-NHL setting and at the present moment, both techniques are complementary.
This article presents the results of a study, started in 2006, on information competency in university students. The study was based on the idea that we should use a semiotic focus of discourse to rethink the traditional understanding of information competency. We argue that information competency is represented in already-existing conditions (cognitive, affective, and pragmatic modalities of understanding). These conditions make it possible to interact in a relative manner with the information. We also developed an in situ method to analyze understanding. This method was tested with a student studying Education at the Universidad Industrial de Santander (Colombia) at a distance. The results show that the dimensions of information competency can be understood based on the subject’s experience. The student showed examples of the clear relationship between the modalities (the semiotic perspective) and the experiences accrued over his or her life (the socio-cultural perspective). The strong relationships between the modalities that required careful analysis of the results were also evident.
Este artículo presenta resultados de un proyecto de investigación cuyo objetivo principal es el fortalecimiento de la sistematización de experiencias (SE) como estrategia de observación y seguimiento de un programa tecnológico de una universidad colombiana. Como metodología se desarrollaron tres procesos consecutivos: propuesta y desarrollo de un estado del arte sobre SE, la determinación de hallazgos de conocimiento teórico, y una reformulación de la estrategia. Los dos primeros se realizaron a través de una metodología particular de revisión y análisis documental; esta metodología permitió determinar y transferir hallazgos en torno al concepto, el enfoque y la justificación de la sistematización de experiencias. Se emiten valoraciones importantes en torno al proceso de análisis categorial de la revisión documental, y la relación e incidencia de los hallazgos de conocimiento frente a la dinámica del contexto de intervención; finalmente, se plantean apuestas en torno a la experiencia investigativa.
* Artículo resultado del proyecto de investigación titulado: "Sistematización de experiencias en educación superior. Estado del arte de la investigación 2005-2011"; proyecto respaldado por la Vicerrectoría de Investigaciones y Extensión de la UIS con código CH2010-2. Fueron colaboradores en este proyecto:
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