Investment in SARS-CoV-2 sequencing in Africa over the past year has led to a major increase in the number of sequences generated, now exceeding 100,000 genomes, used to track the pandemic on the continent. Our results show an increase in the number of African countries able to sequence domestically, and highlight that local sequencing enables faster turnaround time and more regular routine surveillance. Despite limitations of low testing proportions, findings from this genomic surveillance study underscore the heterogeneous nature of the pandemic and shed light on the distinct dispersal dynamics of Variants of Concern, particularly Alpha, Beta, Delta, and Omicron, on the continent. Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve, while the continent faces many emerging and re-emerging infectious disease threats. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century.
Catheter associated urinary tract infection (CAUTI) is one of the most frequently encountered health care associated infections today. Indwelling urinary catheters frequently become colonised with micro-organisms but the majority of cases will be asymptomatic. Differentiation between such colonisation and CAUTI is important for patient management, but unfortunately is not straightforward. This article discusses the diagnosis, causative microbiology and pathogenesis of CAUTI, and briefly considers complications of catheterisation and how these might be prevented.
The recently published update of fungal nomenclature1 generated heated debate on social media with predictions of patient harm and disruption of mycological literature, one example being the following Tweets from the Twitter exchange at [https://twitter.com/ABsteward/status/1313985253405536264] (accession date, 23 October 2020).…
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