Objective To evaluate the association between abnormal ductus venosus (DV) at 11-14 weeks' gestation and chromosomal abnormalities, structural defects and fetal outcome. 2%, 96.9%, 31.3% and 99.3%, respectively, 97.6%, 36.6% and 99.3%, respectively, when Methods DV flow-velocity waveform (DV-FVW) and nuchal translucency thickness (NT) were prospectively evaluated in 1217 singleton pregnancies. Results

SUMMARY OBJECTIVES.Evaluate the feasibility of transvaginal uterine artery Doppler examination in the first and second trimesters of pregnancy, establish reference ranges in a Brazilian population and examine the correlation between these Doppler findings. METHODS. Longitudinal prospective study at the antenatal clinic of a tertiary teaching hospital. Uterine artery Doppler examinations were carried out transvaginally at 11 to 14 weeks and 20 to 25 weeks of gestation. Uterine artery mean pulsatility index (PI) distributions were determined and the presence or absence of an early diastolic notch was also noted. The degree of correlation between first and second trimester Doppler findings was examined. RESULTS. Three hundred and forty four women with live singleton pregnancies and normal outcome were first examined at a mean gestation of 12.7 weeks. The values corresponding to the 50th and 95th centiles of mean PI were 1.69 and 2.48. Bilateral notches were observed in 44% of cases and unilateral notches were present in 19%. Second trimester Doppler examinations were carried out at a mean gestation of 23.2 weeks and corresponding figures for the 50th and 95th centiles were 1.03 and 1.57. Bilateral notches were noted in 4.4% of the cases. First trimester impedance indices were significantly higher and positively correlated to second trimester findings (r = 0.42, p<0.0001). CONCLUSION. Uterine artery Doppler examination can be successfully performed transvaginally and incorporated into scans that are routinely offered to women during their antenatal care in the first and second trimesters. Doppler indices obtained during the first trimester are significantly higher than those of the second trimester and findings at both scans are significantly correlated.

Paulo. O tubérculo genital foi determinado como horizontal ou vertical através do plano sagital e correlacionado com o sexo ao nascimento ou ao resultado do cariótipo quando este foi realizado. Resultados: o sexo fetal determinado pela avaliação ultra-sonográfica coincidiu com o sexo real em 84% dos casos. O sucesso da identificação aumenta com o progredir da gestação, sendo de 72%, 85% e 89% com 11, 12 e 13 semanas, respectivamente. A taxa de acerto também aumenta com o treinamento dos operadores, sendo de 83,5% no início e de 93,6% no final do estudo. Conclusão: por meio da determinação ultra-sonográfica do tubérculo genital podemos predizer o sexo fetal na maior parte dos casos com potencial aplicabilidade na redução das indicações de procedimentos invasivos para detecção de doenças ligadas ao sexo.

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