No abstract

Hot flashes, sleep issues, bipolar disorder, decreased libido, weight gain, and impairments in cognitive performance are all common symptoms of menopause. Herbs and alternative therapies are often of great value to people in the management and treatment of the signs and complications of menopause, due to the adverse effects of hormone therapy. The practices and effects of medicinal plants used in the management of menopausal symptoms are thoroughly reviewed in this article. Clinical investigations have recently demonstrated the efficacy of using many plants and herbs to alleviate menopausal symptoms. Some herbs' traditional uses also have been noted. Medicinal herbs have the potential to exhibit an important role in the treatment of menopausal symptoms; however, further research is needed to back up their efficacy in this domain.

Rat estrous cycle determination or vaginal smear staining is paramount for studies related to endocrinology and reproduction; in the present study; we have reported a simple and rapid method for estrous cycle determination in rats using crystal violet. With this technique, the identification of stages can be done even on the next day. Hormonal variation in blood and histomorphological changes in ovaries at different stages of the estrous cycle were studied in female Wistar rats, which can be used to determine the hormone levels in works related to hormonal drugs, further ovarian morphology can be used to study changes in ovaries during the estrous cycle. This study aims to report a rapid and simple method for vaginal cytology using crystal violet and to report normal hormonal levels and histomorphology of ovaries in various phases of the estrous cycle.

Erratic chronic stresses can lead to the state identical to mental anxiety. The impact of free radicals in the pathogenesis of stress-induced depression is significant. Arecoline alkaloid found in kernels of the Areca catechu seeds, has wide spectrum of biological and pharmacological activities. The objective of this research was to evaluate the protective effect of Areca catechu on chronic unpredictable mild stress prompted variations in behavioral and brain oxidative stress parameters in mice. Areca catechu nuts' antidepressant effect could well be attributed to the alkaloids and saponins found in them, according to physicochemical research. For a period of 2 weeks, the animals were acclimatized and their baseline sucrose preference test was performed. At the termination of the study period, all the animal were exposed to behavioral and biochemical tests. The aqueous extract of Areca catechu nut displayed significant antidepressant activity by forced swim test that was additionally established by the inviolate locomotor actions of animals in the open field and actophotometer activity. Finally, it was concluded that the increase of serotonin and noradrenaline in the areca nut may have an antidepressant impact in chronic unpredictable mild stress.

No abstract