Introduction: Due to its ability to prevent chromosomal damage, the genus Equisetum is likely to have an interesting field of potential use in clinical applications. Objective: To analyze the literature on Equisetum, particularly its anti-inflammatory, antibacterial and cytotoxicity effects, from a dental approach. Methodology: In PubMed, Science Direct, Google Schoolar searched for information with combinations of the keywords: Equisetum, anti-inflammatory, antibacterial, and cytotoxicity. Results: Equisetum possesses anti-inflammatory properties, inhibiting proinflammatory cytokine production and modulating T and B lymphocyte activity. It has antibacterial and antifungal effects against gram positive and gram negative bacteria, including S. mutans and Candida. Administered in controlled doses, toxicity with clinical signs is not detected, however, it shows antitumor effect. Conclusion:Equisetum has anti-inflammatory and antibacterial properties and does not show cytotoxicity, it is a potential therapeutic agent for oral treatments.