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Introduction: Tannerella forsythia, is an anaerobic, Gram-negative microorganism closely related to periodontal disease. Factors such as poor dental hygiene, fixed orthodontic appliances, etc. can cause dysbiosis in the bacterial community. Objective: To analyze the literature about the epidemiology, diagnostic methods, oral manifestations, relationship with systemic diseases and treatment of Tannerella forsythia in orthodontic patients. Methodology: Using the keywords "T. forsythia", "orthodontics", "oral manifestations", "diagnostics", "treatment" and "epidemiology", the main public databases were searched, with emphasis on the last 5 years. It was evaluated with the PRISMA and AMSTAR-2 guidelines. Results: At the national level, in 2019, cases of gingivitis and periodontal disease ranked fifth among the twenty main causes of diseases. As a diagnostic method, most of the studies used molecular biology (PCR) for the identification of bacterial DNA. Very few studies performed cultures for identification. T. forsythia is capable of inducing characteristic signs of gingivitis and periodontal disease. Non-surgical mechanical therapy remains the gold standard in its treatment. There are multiple diseases that can be related to the presence of T. forsythia, so its medical importance becomes more relevant and its control, essential. Conclusion: T. forsythia is closely related to periodontal disease. Its presence is mainly found in the easily accumulated plaque in patients with fixed appliances. It is essential to diagnose it for a treatment that can avoid harm to the patient.

Introduction: Streptococcus gordonii is known as an opportunistic pathogen that can cause local or systemic diseases, such as apical periodontitis and infective endocarditis. Objective: To evaluate Streptococcus gordonii in relation to its prevalence, treatment, diagnostic methods, as well as its endodontic and systemic role. Methodology: A search for information was carried out in databases such as PubM ed, SCOPUS and Google Scholar, using logical operators AND, OR and NOT. We searched for the mention of Streptococcus gordonii bacteria related to the keywords: prevalence, treatment, identification methods, role in endodontics and systemic disease. Results: It is found in teeth with abscesses in 11.1% and in canals with apical periodontitis in 55%. In methods of treatment of the canal system we found that the main irrigant is sodium hypochlorite, lasers and photodynamic therapy. In diagnostic methods we found matrix-assisted laser desorption ionization, Next-Generation Sequencing analysis and PCR. In the cell wall of S. gordonii they act as virulence factors, forming biofilms that can cause apical periodontitis, endocarditis and pneumonia. Conclusion: This microorganism easily adheres to host tissues, forming biofilms that can cause apical periodontitis, endocarditis and pneumonia. It is of utmost importance to raise awareness of its role in order to select the best treatment.

Introduction: Maintaining oral health becomes a challenge when Alzheimer's disease progresses to the intermediate and late stages. Objective: To analyze the literature on Alzheimer's disease and its relationship with dentistry in high impact journals, with a focus on etiology, diagnostic methods, treatment, dental clinical characteristics and dental management. Methodology: The search was carried out in the databases PubMed, SCOPUS and Google Scholar, using the terms "Alzheimer's", "etiology", "diagnostic methods", "treatment", "dental clinical characteristics" and "dental management", together with logical Boolean operators OR and AND. Results: It is important to know that the etiology of Alzheimer's disease is uncertain; the most widely used diagnostic methods for this disease are biomarkers. There is no drug capable of alleviating Alzheimer's disease. It is very common to find different oral diseases due to the lack of hygiene presented by patients suffering from Alzheimer's disease, so it is important to give education to their caregivers to perform oral hygiene. Conclusion: Currently, the issue of the effects of Alzheimer's disease on dentistry has been neglected. It is important to pay more attention to it and to educate caregivers about the possible oral diseases involved in the future as a consequence of poor oral care.