This study examined 3‐year old children and monkeys’ capacities to prepare for immediate future events. In Study 1, children were presented with several tube apparatuses with two exits. When targets were certain to emerge from both, children tended to prepare to catch them by covering each exit. When it was uncertain where targets would emerge, however, they tended to prepare for only one possibility. These results substantiate the claim that simultaneous preparation for mutually exclusive possibilities develops relatively late. Study 2 found no evidence for such a capacity in monkeys (Ateles geoffroyi, Cebus apella, Papio hamadryas) given the same tasks.
Purpose To study the morphometric and morphokinetic profiles of pronuclei (PN) between male and female human zygotes. Method(s) This retrospective cohort study included 94 consecutive autologous single day 5 transfer cycles leading to a singleton live birth. All oocytes were placed in the EmbryoScope + incubator post-sperm injection with all annotations performed retrospectively by one embryologist (L-SO). Timing parameters included 2nd polar body extrusion (tPB2), sperm-originated PN (tSPNa) or oocyte-originated PN (tOPNa) appearance, and PN fading (tPNF). Morphometrics were evaluated at 8 (stage 1), 4 (stage 2), and 0 h before PNF (stage 3), measuring PN area (um 2 ), PN juxtaposition, and nucleolar precursor bodies (NPB) arrangement. Results Male zygotes had longer time intervals of tPB2_tSPNa than female zygotes (4.8 ± 0.2 vs 4.2 ± 0.1 h, OR = 1.442, 95% CI 1.009-2.061, p = 0.044). SPN increased in size from stage 1 through 2 to 3 (435.3 ± 7.2, 506.7 ± 8.0, and 556.3 ± 8.9 um 2 , p = 0.000) and OPN did similarly (399.0 ± 6.1, 464.3 ± 6.7, and 513.8 ± 6.5 um 2 , p = 0.000), with SPN being significantly larger than OPN at each stage (p < 0.05 respectively). More male than female zygotes reached central PN juxtaposition at stage 1 (76.7% vs 51.0%, p = 0.010), stage 2 (97.7% vs 86.3%, p = 0.048), and stage 3 (97.7% vs 86.3%, p = 0.048). More OPN showed aligned NPBs than in SPN at stage 1 only (44.7% vs 28.7%, p = 0.023).
Conclusion(s)Embryos with different sexes display different morphokinetic and morphometric features at the zygotic stage.Embryo selection using such parameters may lead to unbalanced sex ratio in resulting offspring.
Jon Nichol is a reader in History and Education at the University of Exeter. In the 1980s he researched into the application of PROLOG and Knowledge Based Systems to teaching in school and colleges, initially in relation to history but subsequently across the curriculum. During the 1990s he has headed two national research and development projects on the teaching of history to 5-11 and 16-19 year olds.
AbstractTelematics has the potential to transform Higher Education through creating a distributed community of tutors and students. Videotutoring is central to telematics, enabling personal tutoring to occur at a distance. Within the context of a post-graduate teacher training course, videotutoring was used to tutor two students during the first six weeks of their first full-time school placement. Both ends of the videosignal were recorded. Analysis of the tapes used a protocol based upon research into non-verbal communication (NVC). NVC is as important as verbal communication in the tutorial process. Findings suggest that the interaction of participants mediated through the screen was significantly different from face-to-face communication in relation to the twodimensional image of the screen and the "viewing frame" effect of the physical boundaries of the image. The viewing frame literally served as the proscenium arch of a theatre. Two-dimensionality and the viewing frame effect emphasised both the positive and negative elements in inter-personal communication as represented in Argyle's social skills and Goffman's theatrical models. The conclusion is that videotutoring can potentially be a more effective form of tutoring than face-to-face interaction.
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