Today the environmental problem of modern society is the rapid contamination of water resources around the world for pharmaceutical products, including antibiotics. According to the University of York (UK), contamination with antibiotics had covered two-thirds of the waterways of the planet. It was established experimentally that 90 % of antibiotics are applied into the surrounding environment: soil and water. Residues of medical drugs fall into rivers via human waste and animals and through the treatment plant, including pharmaceutical companies. On the other hand, under the influence of antibiotics can significantly change the biocenosis of water bodies. And bacteria gradually become immune to the effects of antibiotics. Therefore, the Ukrainian research Institute of ecological problems in cooperation with the National scientific center Kharkiv Institute of physics and technology experimental studies aimed at inactivation of bactericidal properties of antibiotic solution during processing ozone-air mixture. The study assessed the effectiveness of inactivation of antibiotic ciprofloxacin hydrochloride by methods related to deep oxidation AOPs technologies (Advanced Oxidation Processes) on the basis of combinations of ozonation, UV irradiation, treatment with hydrogen peroxide. Shown the prospects of using ozonation and O3/UV and O3/UV/H2O2 to reduce the toxic effect of the antibiotic residues of ciprofloxacin relative to the test object E. coli in the aquatic environment. Found that ozonation of activated sludge treated with ciprofloxacin, reduces the toxic effect of the antibiotic and promotes the enzymatic activity of the biocenosis of activated sludge.

The paper presents studies of the process of purification of model wastewater, which contained high concentrations of animal proteins, fats and hydrocarbons. The model wastewater solution was treated by biosorption treatment in a bioreactor; with pre-ozonation (O3) and biosorption purification in the bioreactor and in the variant with pre-treatment with ozonation and hydrogen peroxide – by the method of AOPs (O3/H2O2) or the process «Peroxon». The efficiency of cleaning by chemical oxygen consumption when using the AOPs method reached (97-98) %, disinfection – up to 100 %.

Experimental works are devoted to research the efficiency of deamonization and de-nitrogenation of wastewater during treatment in a biodisk installation. Working hypothesis - immobilization of the microbiocenosis can provide simultaneous deep treatment of wastewater from organic compounds and inorganic nitrogen-containing compounds. The purpose of this work is to assess the efficiency of purification of highly concentrated organic pollutants and mineralized wastewater from nitrogen compounds in a biodisk installation and to determine the main ecological-trophic groups of microorganisms included in the immobilized nitrogen-transforming microbiocenosis. Methods of research of immobilized microbiocenosis - microbiological. physiological, biochemical (inhibitory experiments), natural and model wastewater - hydrochemical. It has been established that in microbiocenosis immobilized on disks conditions that allow heterotrophic and autotrophic microorganisms to actively metabolize organic and inorganic compounds under aerobic and anoxidic conditions are created. The quantitative indicators of the influence on the kinetics of the processes of the concentration of organic substances in the treated wastewater have been determined. On the basis of microbiological, physiological and biochemical studies in the immobilized microbiocenosis, ammonium-acid bacteria (and, possibly, archaea) nitrite-acid and denitrifying bacteria were found, and in the absence of organic substances in the environment - anammox bacteria. Moreover, in the biofilm that was formed in the absence of organic substances in the environment, the activity of anammox bacteria in deamonization significantly exceeded the activity of ammonium oxidizing bacteria and archaea. The obtained results and quantitative requirements were used in the organization of real wastewater treatment in a biodisc plant in industrial conditions.

Today, most surface waters of Ukraine are eutrophied due to the entry into water bodies of a significant amount of nutrients – compounds of carbon, nitrogen and phosphorus. Nitrogen and phosphorus enter water bodies with wastewater, sewage from agricultural lands and livestock farms, as well as with precipitation, due to the decomposition of water biomass, aquatic vegetation and zoocenoses. In the presence of free carbon dioxide (the concentration of which depends on bicarbonate alkalinity and water pH) and at certain rates of biochemical oxygen utilization (BOD) 7.2 g of nitrogen and 1 g of phosphorus produce 115 g of algae, which decomposition then consumes 115 g of oxygen [1].

the action of Rizostim, the content of the sum of chlorophylls a and b was 8,03 mg/g dry weight, which was 23,7 % higher than the control value, the content of chlorophyll a and chlorophyll b-5,23 mg/g dry weight and 2,80 mg/g of dry weight, which is by 24,7 % and 21,6 % more than the control indicators, respectively. The highest yield of sweet pepper was found in the processing of seeds of Rizostim and 39,4 t/ha were obtained, which in turn exceeded the value of control by 59,5 % respectively. Thus, a more effective growth regulator for growing sweet peppers is the preparation Rizostim. It may be recommended for agricultural practice for the presowing treatment of pepper seeds.