We performed a prospective study to examine whether the IgA antibodies against cholera that are present in breast milk protect breast-fed infants and children against colonization with Vibrio cholerae 01 and disease. Among families of patients with cholera, we collected breast milk from mothers who had not had diarrhea in the previous week and monitored them and their breast-fed children for cholera colonization and diarrhea for 10 days. Breast milk was assayed for IgA antibodies to cholera toxin and lipopolysaccharide. Ninety-three mother--child pairs were studied; 30 infants became colonized with V. cholerae 01 and disease developed in 19. There were no differences between the antibody levels in milk fed to children who became colonized and in milk fed to children who did not. However, among the children who became colonized, those who had diarrhea drank breast milk containing significantly lower levels of both kinds of cholera antibodies than were present in the milk consumed by children who had no symptoms. We conclude that breast-milk antibodies against cholera do not appear to protect children from colonization with V. cholerae 01 but do protect against disease in those who are colonized.

Purpose. To assess the relationship between breast-feeding and the risk of life-threatening rotavirus diarrhea among Bangladeshi infants and children younger than 24 months of age. Design. Case-control study. Setting. A rural Bangladesh community. Participants. One hundred two cases with clinically severe rotavirus diarrhea detected in a treatment centerbased surveillance system during 1985 and 1986, and 2587 controls selected in three surveys of the same community during the same calendar interval. Outcomes. Cases and controls were compared for the frequency of antecedent breast-feeding patterns. Results. Compared with other feeding modes, exclusive breast-feeding of infants was associated with significant protection against severe rotavirus diarrhea (relative risk (RR) = 0.10; 95% confidence interval [CI] = 0.03,0.34). However, during the second year of life, the risk of this outcome was higher in breast-fed than in non-breast-fed children (RR = 2.85; 95% CI = 0.37,21.71), and no overall protection was associated with breast-feeding during the first 2 years of life (RR = 2.61; 95% CI = 0.62,11.02). Conclusions. Although exclusive breast-feeding appeared to protect infants against severe rotavirus diarrhea, breast-feeding per se conferred no overall protection during the first 2 years of life, suggesting that breast-feeding temporarily postponed rather than prevented this outcome. While not detracting from efforts to promote breast-feeding to alleviate the burden of diarrhea due to nonrotaviral enteropathogens, our findings cast doubt on whether such efforts will impact on the problem of severe rotavirus diarrhea.

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This article investigates the features of heat and mass transfer for the steady two-dimensional Williamson nanofluid flow across an exponentially stretched surface depending on suction/injection. The boundary conditions incorporate the impacts of the Brownian motion and thermophoresis boundary. The analysis of heat transfer is carried out for the two cases of prescribed exponential order surface temperature (PEST) and prescribed exponential order heat flux (PEHF). The ongoing flow problem is mathematically modeled under the basic laws of motion and heat transfer. The similarity variables are allowed to transmute the governing equations of the problem into a similarity ordinary differential equation (ODEs). The solution of this reduced non-linear system of ODEs is supported by the Homotopy analysis method (HAM). The combination of HAM arrangements is acquired by plotting the h-curve. In order to evaluate the influence of several emergent parameters, the outcomes are presented numerically and are plotted diagrammatically as a consequence of velocity, temperature and concentration proles.

In the current millennium, consumers are becoming more conscious about their dietary patterns with special concern to nutrient retention during cooking methods. There is a need to assess the most convenient and nutritionally better thermal cooking method which causes the least nutrient abuse. The current study investigated the consequence of three cookery methods viz. conventional boiling, steaming and microwave cooking on the physical parameters, β-carotene, vitamin C, total phenolic contents (TPC), total flavonoid contents (TFC) and antioxidant activity (DPPH%) of the particular vegetables. Results revealed that both cooking methods and length of time exerted positive and negative influence on nutritional composition of vegetables. L*, a* and b* values decreased in all samples. In texture analysis, highest force N (Newton) determined in control and microwave cooked samples followed by steaming and boiled samples. Cooking of vegetable by microwaving had the maximum retention for vitamin C, TPC and DPPH% after control. While, ß-carotene contents increased in microwave cooking than control. Total flavonoid contents were tending to a decreasing trend in all cooking methods but highest contents were retained in boiling cooking. Amongst the three cookery methods adopted, microwave cooking method emerged as the most appropriate method in terms of retention of nutrients in vegetables.