Medical students have been responsible for organizing the majority of new PDT. To ensure quality and sustainability, however, faculty must play a more central role in the planning and implementation of such training programs. Medical schools must continue to reevaluate how best to maximize global health electives for trainees and the communities in which they study. PDT offers one avenue for schools to ensure that students are safe and socially accountable during their time abroad.
Purpose
To evaluate ocular hypertension (OHT) after Ozurdex injection to determine the incidence of OHT, therapy of OHT, and any associative factors such as diagnosis, underlying glaucoma and therapy, or sequential Ozurdex injection(s).
Methods
Retrospective consecutive case series with patients receiving one or more intravitreal Ozurdex implantations at a tertiary care academic center. OHT was defined as a single measurement of ≥30 mmHg, or an increase of ≥10 mmHg from baseline.
Results
Ninety-four injections in 52 patients (59 eyes) were reviewed. Forty eyes received a single injection, and 19 eyes received multiple injections. OHT developed in 14 patients (26.9%). Thirteen patients (25%) had pre-existing glaucoma or glaucoma suspicion, and six of these developed OHT. Glaucoma eye drops were initiated following 13 injections (13.8%). Invasive glaucoma surgery was required in three patients (3.2%): all had glaucoma or glaucoma suspicion (one case was related to neovascular glaucoma and unlikely related to steroid response after Ozurdex). There was no difference in relative IOP increase (i.e. difference between final follow-up or subsequent intravitreal injection versus baseline) between single versus multiple Ozurdex injections (P = 0.883).
Conclusions
26.9% of patients who received Ozurdex developed OHT. Glaucoma or glaucoma suspicion factors were present in all patients who required invasive glaucoma surgery. A greater proportion of patients who received multiple injections had an IOP elevation, but the relative IOP increase was not significant.
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