Introduction: Menorrhagia is a common gynaecological problem and its cause remains unexplained in a significant proportion of females.Aim: The present study was done to diagnose a wide range of haemostatic disorders which can give rise to menorrhagia in women of adolescent, postadolescent and perimenopausal age group.

IntroductionAbnormal bleeding may result from deficiency of one of the clotting factors.Case presentationA 13-year-old Indian girl, presented with a history of bleeding following minor injury, epistaxis, and hematuria, bleeding from gums, subcutaneous bleeding and gastro intestinal tract bleeding. She underwent a complete coagulation profile test, CT scan and ultrasound. Platelet Factor 3 dysfunction was diagnosed to be the cause of bleeding. Patient was transfused fresh frozen plasma and platelet as part of treatment. Condition of the patient after four months of diagnosis deteriorated and she started bleeding in tears and sweat.ConclusionA thorough examination and proper workup are necessary to determine the exact cause and rule out serious conditions.

Objective To evaluate the incidence of hereditary bleeding disorders, registered at our centre from all over Uttar Pradesh over an extended period of 10 years.Material and methods A complete coagulation profi le of 240 cases conducted, followed by clinical history of the patient. The frequency and type of bleeding, age of onset, treatment taken, consanguinity and the blood transfusion if any, are little information collected from the patient.

IntroductionHemophilia is uncommon in females and there is little knowledge about the clinical manifestation.Case presentationWe report here an unusual case of three hemophilic females diagnosed as factor IX deficient. Normal reports of ultrasonography (USG) and relevant endocrine investigations conducted in two adult females ruled out any usual gynecological and endocrinal causes of bleeding. Complete coagulation profiles were conducted and diagnosed these female bleeders to be hemophiliacs suffering from factor IX deficiency.ConclusionFemales presenting with menorrhagia and bleeding from other sites without any discernable cause require proper evaluation for congenital coagulation disorders. In the present case series, females are diagnosed factor IX deficient (Hemophilia B).