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Objectives: To study, the bacterial profile in cases of neonatal sepsis admitted to the neonatal nursery or neonatal intensive care unit (NICU) and to identify the risk factors for early-onset neonatal sepsis. Design: Retrospective survey of hospital records from January 2012 to December 2012. Setting: A neonatal unit of a rural medical college hospital. Subjects: All inborn and outborn neonates who either had clinical signs of sepsis or were born to mothers with risk factors for sepsis and underwent a sepsis screen. Neonatal sepsis was defined as positive blood culture in babies younger than 1 month of age who had clinical signs of sepsis or had maternal risk factors for sepsis. Results: 396 neonates were screened for sepsis during the study period, of which 64 (16%) were culture positive. Of these, 42 (65.6%) had early-onset sepsis while 22 (34.3%) had late-onset sepsis (LOS). There were 6 deaths among those who had sepsis (9.3%). The predominant organisms in both early and LOS were Klebsiella and Staphylococcus aureus followed by Escherichia coli. Conclusion:The pattern of isolates is more or less similar to that seen in other NICU across the country. Klebsiella and S. aureus were two of the commonest organisms isolated in our study.

Background- Newborn infants are unique in their physiology and the health problems that they experience. Neonatal period is dened from birth to under four weeks of age. Late preterm infants may physiologically and physically appear like infants born at term, but most late preterm infants may undergo complications like respiratory distress, apnea, hypothermia, feeding problems, hypoglycemia, hyperbilirubinemia, sepsis, and mortality. AIM-To compare the clinical prole of late preterm neonates with term neonates. MATERIALAND METHODS: This prospective observational study was carried out in neonatal division of department of pediatrics MMIMSR, Mullana. Eligible neonates delivered at MMIMSR, Mullana born from 34 weeks up to 42 weeks gestation were included. All infants enrolled in the study was followed daily till rst 7 days of life for any morbidity by clinical evaluation and review of hospital records.104 preterms included in the study and 226 term neonates were included in the study. Results- Preterms born via LSCS and NVD were(58%vs.42%).Morbidities in late preterms were Hypoglycemia (21.2% vs. 9.3%), Hypothermia (15.4%vs5.7%), hypocalcaemia (38.4% vs. 5.3%), neonatal hyperbilirubinemia(67.3% vs. 30.5%), feeding difculties(44.2% vs. 14.6%), sepsis(40.4% vs. 19.5%), respiratory support(53% vs. 47%)