Background: Achromobacter is a ubiquitous, non-fermenting, Gram-negative bacterium that lives in soil and aquatic environments. In recent years, many studies have shown its potential as opportunistic pathogen. It can colonize various items used in hospital and can survive various disinfectants. The infections get complicated due to its vast spectrum of intrinsic and extrinsic resistance to antimicrobial agents and disinfectants. Achromobacter spp. is an emerging pathogen and is becoming a reservoir for horizontal genetic transfer elements involved in spreading antibiotic resistance. This study was conducted to assess the extent of the Achromobacter related infection in our hospital setting and to set a baseline for future studies.Methods: This study was conducted over a period of one year (January to December 2018) in our tertiary care hospital. All specimens submitted for aerobic culture and sensitivity were analyzed and the bacterial identification and antibiotic sensitivity of the isolates was carried out using automated method (Vitek 2 Compact, bioMerieux).Results: Achromobacter species was reported from 0.46% (63/13831) specimens, 40% of them were isolated from suction tips. Achromobacter denitrificans amounted for 47/63 (74.6%) while Achromobacter xylosoxidans was identified in 16/63 (25.4%).Conclusions: Studying the organisms in order to observe their changing trends
Background: Viral hepatitis is a global health problem with 170 million Hepatitis C Virus (HCV) carriers worldwide, and 12-13 million HCV carriers in India. Unscreened blood and components play a significant role in transmission of HCV apart from reuse of injection needles, unsterilized surgical equipments and vertical transmission from mother to child. Unsafe blood transfusion not only poses risk to patients, causing significant morbidity and mortality, but also adds to the economical burden on healthcare system. Aims and Objectives: Aim of this study is to estimate the seroprevalence of HCV infection among the voluntary and relative donors over a period of 7 years at blood banks of Madhya Pradesh with collaboration of Madhya Pradesh State AIDS control Society (MPSACS) Bhopal, India from 2011 to 2017. Materials and Methods: This is a retrospective study of blood donation at blood banks, of Madhya Pradesh, India. Blood units were screened for TTIs from January 2011 To December 2017. HIV, HCV and HBV tests were done by ELISA. Data of HCV was collected and compared statistically by frequency distribution and percentage proportion. Chi Square (χ 2) test was used to determine the significant difference statistically. Results: The mean age of donors was 32.4 2 ± 8.63 years. Major contribution was from male donors (93.8%). Majority of donation was done voluntarily (87.3 %). Out of the total 1,876,219 donors tested for TTIs over 7 years, 1980 (0.11%) were positive to anti HCV (p=.000001). Conclusion: The prevalence of HCV infection was 0.11% among blood donors of Madhya Pradesh, with geographic variation among districts. Aiming to provide safe blood to the patients, prevention of transmission of HCV by proper donor counseling and screening of the unit is required.
Kluyvera is a relatively new genus, belonging to family Enterobacteriaceae. This organism colonizes mainly respiratory and gastrointestinal tract. It has also been reported from various environmental sources. Due to a rise in immune-compromised states and ease of identification using automated methods rare organisms are now being reported with their role as potential opportunistic pathogens. Meticulous detailed identification and reporting of pathogens like Klyuvera to differentiate it from other members of Enterobacteriaceae can lead to solving the pathogenic importance of such organisms. We report a case of bilateral gluteal abscess due to Kluyvera cryocrescens in an obese diabetic adult male.
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