Background: End-stage renal failure is one of the widespread diseases requiring hemodialysis renal replacement therapy. However; patients on maintenance hemodialysis usually suffer from fatigue. A recent growing interest is directed at applying non-pharmacological alongside traditional methods for managing such chronic complaints. Therefore, this study aimed to evaluate the effect of deep breathing exercise training on level of fatigue among maintenance hemodialysis patients. Materials and Method: This study is a randomized quasi-experimental design with parallel groups. One hundred hemodialysis patients participated in the study. They were admitted to the Hemodialysis Department of Alexandria Main University Hospital. The patients were randomly and equally assigned to either the control group or the intervention group (n=50 each). Fatigue was measured in both groups; before and four weeks after nursing intervention using Fatigue Assessment Scale (FAS). Results: Prior to deep breathing exercises, the total mean percent score of fatigue in the intervention group was 66.30±12.19 compared to 62.80±13.12 in the controls. After four weeks of performing the exercise; the mean score was dramatically decreased to 26.25±5.47 in the intervention group compared to 61.40±11.06 in the control. Additionally, a statistically significant difference within the intervention group was declared before and after the intervention (P<0.001). Conclusion:Performing deep breathing exercises for twenty minutes, twice per day for a full month; can reduce maintenance hemodialysis patients' fatigue level.

Background:Patient safety measures are directed to prevent or minimize complications and adverse event incident that needs the collaboration of all health staff. Nurses have a significant role in improving patient safety as major personnel dealing continuously over 24 hours with the patients. Aim of the study: Assess nurses' awareness, commitment, and attitudes regarding patient safety measures. Subjects and Method: Research design: A cross-sectional, descriptive design was utilized. . Setting:The study was conducted at Medical-Surgical Units of Zagazig university hospitals . Subject: A convenient sampling of 100 nurses selected from theses units in the period of March to January 2021. Tools of data collection : Two tools were used for data collection. Tool (I): A structured interviewing questionnaire that included four parts: demographic characteristics of participants, nurses' awearness, commitment, and attitude's regarding patient safety measures. Tool (II): was perceived implicit rationing of nursing care. Results: the majority of participants were females, about two third had technical nursing institute, with professional experience ranging from six to ten years, nearly two-thirds worked for more than 36 hours weekly, less than half didn't receive training courses regarding patient safety, more than three quarters reported that safety measures were excellent and had total satisfactory awareness regarding patients safety, nearly to half had high commitment level score, less than two-thirds had total positive attitudes, only half had a satisfactory total safety practices knowledge level score, more than quarter were rating missed nursing care as high and or moderate. A statistically significant difference and positive correlation were found between the demographic characteristics of participants and their awareness' level scores as well as with safety commitment, attitudes, and missed nursing care.Conclusion : Gaining confirmation regarding the level of nurses' awearness, commitment, and attitudes, toward patient safety measures are significant to undertake the essential strategies required to minimize the burden of health care, and its related effects. Recommendations:Continuously training on patient safety measures must be provided to nurses to be proficient, devoted, updating regarding patients' safety measures.

Background: Women with breast cancer often are treated with some kind of surgery such as a mastectomy which affects moving the shoulder and arm or going about daily activities, like dressing, bathing, and combing hair. Pain and stiffness can cause weakness and limit movement of your arm and shoulder. Exercise can help get movement back. Aim:  To investigate the effect of instructional guidelines regarding post-operative activity and mastectomy exercises on breast cancer women's knowledge. Design: A quasi-experimental design was used to accomplish this study (pre/post-test). Setting: The research will be carried out in the Oncology Inpatient and Outpatient clinic at Beni-Suef University Hospital, Egypt. Subject: The study subjects included a convenient sample of 100 women after mastectomy. Tools: Four tools were used Tool 1: Structured interviewing questionnaire: developed by the researchers to assess patient demographic, clinical data, and knowledge, Tool 2: Activities of Daily Living scales, Tool 3: The Pain Disability Index, and Tool 4: Observational checklist. Results: The results revealed that there was a positive significant correlation (P<0.001) between post-mastectomy women's knowledge scores pre and post-instructional guidelines implementation. There were highly significant improvements in post-mastectomy women's knowledge and post-operative activity and mastectomy exercises pre and post-instructional guidelines implementation (P<0.005).

Background: Medication adherence and Quality of Life (QoL) are two integral factors for sustaining optimal health; where medication non-adherence of Hepatitis C virus patients predisposes them to poor prognosis and remarkably low QoL. This study aimed to explore the effect of medication adherence practices on the quality of life among newly treated hepatitis "C" virus (HCV) patients. Methods: The researchers used a quasi-experimental research design. Setting: The study was conducted at the Hepatology Outpatient Clinic of Alexandria Main University Hospital. Subjects: A purposive non-probability sample of 100 adult newly treated HCV patients (≤12 months) were enrolled. Tools: The researchers used three tools for collecting data. Firstly, Sociodemographic and Clinical Data sheet, secondly Morisky Medication Adherence Scale 8 items (MMAS-8), and thirdly, the World Health Organization Quality of Life abbreviated version (WHOQoL-BREF) Questionnaire. Results: A highly significant difference was obvious between all medication adherence items of studied patients at the pre, one-month, and three months post-tests. Where the mean total QoL score was increased after three months of follow-up than from the preintervention with a highly significant difference. Additionally, a highly positive correlation between medication adherence and QoL was detected in pre, one-month, and three months follow-up periods. Conclusion: the mean total QoL score of the studied HCV patients was improved, with a high positive correlation between medication adherence and QoL in newly treated studied HCV patients.

Medication adherence and Quality of Life (QoL) are two integral factors for sustaining optimal health; where medication non-adherence of Hepatitis C virus patients predisposes them to poor prognosis and remarkably low QoL. This study aimed to explore the effect of medication adherence practices on the quality of life among newly treated hepatitis "C" virus (HCV) patients. Methods:The researchers used a quasi-experimental research design. Setting: The study was conducted at the Hepatology Outpatient Clinic of Alexandria Main University Hospital. Subjects: A purposive nonprobability sample of 100 adult newly treated HCV patients (≤12 months) were enrolled. Tools: The researchers used three tools for collecting data. Firstly, Sociodemographic and Clinical Data sheet, secondly Morisky Medication Adherence Scale 8 items (MMAS-8), and thirdly, the World Health Organization Quality of Life abbreviated version (WHOQoL-BREF) Questionnaire. Results: A highly significant difference was obvious between all medication adherence items of studied patients at the pre, one-month, and three months post-tests. Where the mean total QoL score was increased after three months of follow-up than from the pre-intervention with a highly significant difference. Additionally, a highly positive correlation between medication adherence and QoL was detected in pre, one-month, and three months follow-up periods. Conclusion: the mean total QoL score of the studied HCV patients was improved, with a high positive correlation between medication adherence and QoL in newly treated studied HCV patients.