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Diabetic Nephropathy (DN) poses a major health problem. There is strong evidence for a potential role of the eNOS gene. The aim of this case control study was to investigate the possible role of genetic variants of the endothelial Nitric Oxide Synthase (eNOS) gene (VNTR) in the pathogenesis of nephropathy in patients with diabetes mellitus. The study included 196 subjects (145 T2DM and 51 normal controls) T2DM were classified into 2 groups: 97 diagnosed with DN, and 48 diabetics without nephropathy and hypertension as +ve control. Randomly selected was conducted to assess the association of SNP eNOS intron 4a/b VNTR polymorphism gene with diabetic nephropathy in Iraqi population. Blood samples from subjects and controls were analyzed to investigate the eNOS genotypes No significant differences were found in the frequency of eNOS genotypes between diabetic patients (either in group 1 or group 2) and controls (p >0.05). Also, no significant differences were found in the frequency of eNOS genotypes between group 1 and group 2 (p >0.05).

Background: The most common endocrine illness that affects older women with childbearing age is Polycystic ovary syndrome (PCOS). The prevalence ranges from 8%-13% according to the definitions used and residents utilized. Materials and methods: Illness with the infertile ovarian syndrome and a medical referral were studied to Al Hussain Educational Hospital to the infertility center during the period from August to November 2017. The diagnosis of the illness was serene under the supervision of gynecologists and according to clinical indications. Laboratory discovery. This project investigated 80 healthy people and 90 illness with polycystic ovary syndrome. Hormone levels, including prolactin, TSH, FSH and TSH, and blood samples were measured, and the IL-6 level concentration was examined. Results: Results exemplify that there was no important alteration between illness and controls regarding age, TSH, and prolactin, while the LH and estradiol were suggestively advanced in illness in comparison to controls, P-value andGLT;0.001. The FSH and progesterone were suggestively lesser in illness as compared to controls, p-value ≤ 0.001. Results displays that there was an important difference of IL-6 altitudes in illness comparison to controls, P-value andGLT;0.001. Conclusion: This indicates the close connotation between the ovary and pituitary axis. The polycystic ovary syndrome is an inflammatory illness that will lead to the rise of many inflammatory cytokines such as; IL-6.

In the current study, we investigated the correlation between serum s-adenosylhomocysteine as a new marker for myocardial infarction severity with homocysteine, troponin, vitamin B6 and B 12 on 90 acute myocardial infarction patients and 120 normal persons as control.The data of all patients and controls were measured by using the ELISA technique except troponin was measured by using the VIDIS technique, while the data were analyzed by SPSS software. The results of this study show a significant increase in s-adenosylhomocysteine, troponin, homocysteine, while vitamin B6 and B12 were decreased significantly.The correlation study proved that s-adenosylhomocysteine as a golden marker for AMI patient for male and female-specific with SEAMI while troponin with high correlation in NSEMI.