As queimaduras são lesões decorrentes de fontes variadas capazes de danificar os tecidos corporais e acarretar a morte celular. A identificação do grau da queimadura de acordo com a profundidade e extensão do local atingido é de extrema

The use of medication during pregnancy and lactation is a subject of extreme relevance, since the scarcity of research with these groups makes it difficult to access data on the possible effects and risks of drugs. The objective of the current study seeks to analyze the use of drugs in pregnant and breastfeeding women attended at the Basic Health Units in the central region of the Federal District and classify the risk of such drugs according to the Food and Drug Administration. In this research, data were collected through a questionnaire using Google Forms. The research took place between August 2020 and July 2021, through bibliographic analysis and data collection from the questionnaire. The results showed that 34% of the women were lactating and 66% were pregnant and 100% had some medical prescription, including folic acid, ferrous sulfate and multivitamins. The rate of selfmedication was high, 22%, with analgesics, antipyretics and antiemetics being the most used therapeutic classes. The use of drugs by these women was predominant in the first trimester, followed by the second and third, and they were being monitored by medical assistance. Given these results, we concluded that health professionals were cautious when prescribing medications, demonstrating a rational prescription. However, the relevance of the production of campaigns by the Basic Units is highlighted, alerting and guiding professionals in the area to pay attention to the care in drug prescriptions, as well as the women in this group about the possible effects, in addition to emphasizing the risks of self-medication. This way, we will avoid prescription errors and, consequently, damage to the health of the pregnant woman, fetus and child.

Analysis of the number of syphilis hospitalizations in elderly women in Brazil between 2010 and 2019 by age group

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RESUMOObjetivo: avaliar a relação entre a síndrome de Down e os fatores de risco para a infecção e gravidade da COVID-19, em pacientes pediátricos. Métodos: trata-se de uma revisão narrativa. Resultados: Na patologia da Covid-19 vê-se que a mortalidade e morbidade oriunda da infecção tem íntima relação com a resposta imune exacerbada. Na síndrome de Down (SD) há uma triplicação dos genes codificados pelo cromossomo 21, promovendo uma desregulamentação da transcrição de genes em todo o DNA especialmente com a produção dos interferons IFNAR1, IFNAR2, IFNGR2 e IL10RB, contribuindo para uma resposta imunológica exacerbada, influenciando na resposta viral do Sars-Cov-2 e na sinalização celular do processo inflamatório. Conclusão/Considerações finais: Pacientes com SD, devido a vários fatores, entre eles a desregulação imune, possuem um risco aumentado de infecção pela Covid-19, o que, por sua vez, conduz a uma maior incidência de morbimortalidade. Há necessidade de se buscar, assim, soluções de prevenção e condução diferenciadas para os portadores de Trissomia do 21 infectados pelo Sars-CoV-2.Palavras-chave: Síndrome de down, Infeccções por coronavírus, Pediatria, Citocinas.