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This paper presents an overview of the image analysis techniques in the domain of histopathology, specifically, for the objective of automated carcinoma detection and classification. As in other biomedical imaging areas such as radiology, many computer assisted diagnosis (CAD) systems have been implemented to aid histopathologists and clinicians in cancer diagnosis and research, which have been attempted to significantly reduce the labor and subjectivity of traditional manual intervention with histology images. The task of automated histology image analysis is usually not simple due to the unique characteristics of histology imaging, including the variability in image preparation techniques, clinical interpretation protocols, and the complex structures and very large size of the images themselves. In this paper we discuss those characteristics, provide relevant background information about slide preparation and interpretation, and review the application of digital image processing techniques to the field of histology image analysis. In particular, emphasis is given to state-of-the-art image segmentation methods for feature extraction and disease classification. Four major carcinomas of cervix, prostate, breast, and lung are selected to illustrate the functions and capabilities of existing CAD systems.

], prescribed mean curvature flow [Hildebrandt and Polthier 2004], mean filtering [Yagou et al. 2002], bilateral normal filtering [Zheng et al. 2011], our method. The wireframe shows folded triangles as red edges. AbstractWe present an algorithm for denoising triangulated models based on L0 minimization. Our method maximizes the flat regions of the model and gradually removes noise while preserving sharp features. As part of this process, we build a discrete differential operator for arbitrary triangle meshes that is robust with respect to degenerate triangulations. We compare our method versus other anisotropic denoising algorithms and demonstrate that our method is more robust and produces good results even in the presence of high noise.

In this paper, we introduce the Variational Autoencoder (VAE) to an end-to-end speech synthesis model, to learn the latent representation of speaking styles in an unsupervised manner. The style representation learned through VAE shows good properties such as disentangling, scaling, and combination, which makes it easy for style control. Style transfer can be achieved in this framework by first inferring style representation through the recognition network of VAE, then feeding it into TTS network to guide the style in synthesizing speech. To avoid Kullback-Leibler (KL) divergence collapse in training, several techniques are adopted. Finally, the proposed model shows good performance of style control and outperforms Global Style Token (GST) model in ABX preference tests on style transfer.