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With the introduction of radioimmunoassay (RIA) techniques, it has become toxicologically possible to determine drug concentrations in postmortem vitreous humor. This study demonstrates and confirms this toxicological feasibility. In 49 medical examiner's drug related cases, postmortem tissue levels of morphine, barbiturates, and methadone were compared to the vitreous humor.

In recent years radioimmunoassay has provided the toxicologist with a rapid, simple way to identify and quantitate drugs of abuse. This paper deals with an evaluation of a radioimmunoassay for methadone.

In 1967 a routine alcohol determination was performed on the brain and blood of a 43-year-old male (HVB) who had been found unconscious, lying at the foot of a stairway in his home. He had sustained a fracture of the skull and survived nine hours in the hospital.

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