The synthesis and characterization of a copper complex with glimepiride (an oral antidiabetic drug) has been studied. The conductometric titration using monovariation method indicates that complex is non-ionic and of ML 2 type.Analytical data agrees with the molecular formula (C 24 H 34 N 4 O 5 S) 2 Cu. Structure of the complex was assigned as square planar in which ligand molecules lies horizontally joining the central copper atom. Infrared, Mass spectral and particle size analysis had confirm the coordination of sulphonyl oxygen on one side and enolic oxygen attached from other side with the metal ion. The structure for complex was proposed on the basis of analytical data and elemental analysis.

ABSTRACT. In this paper, we describe the reactivity of our previously reported (η 3 -allyl)dicarbonylnitrosyl iron complexes (1-9). In this context, stoichiometric reactions of 1-9 with dimethyl malonate and di-iso-butyl malonate were carried out. The regioselectivity of the resulting products (10-25) was determined by gas chromatoraphic analysis of reaction mixtures. These products were purified by column chromatography and then structurally characterized by IR, 1 H NMR, 13 C NMR spectroscopies and mass spectrometry. Effect of different ligands L (L = CO, PPh3, SIMES (1,3-di-tert-butylimidazolium hexafluoro phosphate), BUSI(1,3-bis(2,4,6-trimethyl-phenyl)-4,5-dihydro-3H-imidazol-1-ium hexafluorophosphate)) and their influence on the substitution pattern has also been studied. The introduction of variable substituents exhibited diverse reactivities. Generally, it was observed that the reactivity decreased by increasing the size of substituentin (η 3 -allyl)dicarbonylnitrosyl iron complexes (1-9). Strong impact on the reactivity was observed due to substitution pattern of the allyl moiety. A considerable reduction in the conversion ratio from 81% to 68% was observed in repositioning the substituent from C-3 to C-2 position.

Antioxidants are wisely employed in various food products, physiology and pathology for controlling different oxidative routes. Natural antioxidants should replace synthetic ones since they are destructive for human’s health. In this regard, corn silk extract (CSEE) was obtained and subsequently screened for antioxidant potential by different assays (DPPH, β-carotene, FRAP, ABTS, total phenol CSE and flavonoids content). Cu(II) and Zn(II) chelates of this extract were also prepared to compare their antioxidant potential with uncomplexed extract. Stabilization of sunflower oil by CSEE and its respective chelates [CSE-Cu(II) and CSE-Zn(II)] at variable concentrations (250 ppm, 500 ppm, 1000 ppm) was investigated by applying three parameters, like PV, FFA and IV values. The results were compared with synthetic standards such as BHA and BHT. BHT and CSEE 1000 ppm possessed maximum oil stabilizing capacity.