Background: The high prevalence of DM, as well as drug interaction problems that increase 2.5 times for each patient prescription and the side effects of individuals with diabetes mellitus including being more susceptible to drug interactions, it is necessary to monitor drug therapy in diabetes patients Mellitus. Methods: in this study, this research uses a literature study or uses a systematic literature review or also known as descriptive analysis based on research data. Results: This study shows that the use of expert systems in pharmacy, especially for disease detection and drug interactions, has been widely developed and proven to be able to detect.
Conclusion: Based on the results and discussions that have been obtained, it can be concluded that the expert system is very useful for detecting disease and is also useful for checking drug interactions with a treatment therapy.
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