3.2% of admissions was caused by ADEs. 2.2% of hospitalized patients experienced ADEs. 62% of ADEs were potentially preventable. A high proportion of preventable ADEs were around a small number of drugs. Effective safety practices directed to reduce the incidence of medication errors are needed.

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Atrial fibrillation (AF) is the most frequent arrhythmia worldwide and it is associated with increased risk of stroke, thromboembolism and mortality. 1 Nevertheless, these risks can be reduced by using oral anticoagulation (OAC), both Direct Oral Anticoagulants (DOACs) or Vitamin K Antagonists (VKAs). 2 Despite the increasing use of DOACs, VKAs (mainly warfarin and acenocoumarol) are still widely used for stroke prevention in AF in several countries. Notwithstanding, the efficacy and safety of VKAs depend upon the quality of anticoagulation control, as reflected by the average time in therapeutic range (TTR) of international normalised ratio (INR) 2.0-3.0.

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