Biomimetic remineralization is an approach that mimics natural biomineralization, and improves adhesive procedures. The aim of this paper was to investigate the influence of Dentin Caries-like Lesions (DCLL)-Producing Model on microtensile bond strength (μTBS) of etch and rinse adhesive systems and investigate the effect of remineralizing agents such as Sodium Fluoride (NaF), MI Paste™ (MP) and Curodont™ Repair (CR) on caries-affected dentin (n = 6). Nine groups were established: (1) Sound dentin; (2) Demineralized dentin/Chemical DCLL: (3) Demineralized dentin/Biological DCLL; (4) Chemical/DCLL + NaF; (5) Chemical/DCLL + MP; (6) Chemical/DCLL + CR; (7) Biological/DCLL + NaF; (8) Biological/DCLL + MP; (9) Biological/DCLL + CR. Then all dentin blocks were subjected to a bonding procedure with Adper™ Single Bond 2 adhesive system/Filtek Z350XT 4 mm high block, following this they were immersed in deionized water/24 h and then sectioned with ≅1 mm2 beams. The μTBS test was conducted at 1 mm/min/500 N loading. Failure sites were evaluated by SEM (scanning electron microscopy (150×). μTBS data were submitted to factorial ANOVA and Tukey’s test (p < 0.05). The highest values were found when demineralized dentin was treated with MP and CR, regardless caries lesion depth (p < 0.05). There was a predominance of adhesive/mixed in the present study. It was concluded that the use of the artificial dentin caries production models produces differences in the μTBS. Additionally MP and CR remineralizing agents could enhance adhesive procedures even at different models of caries lesion.

Bonding to demineralized dentin of a diseased tooth has shown to be a significant clinical issue. This study evaluated the effect of 0.2% NaF-(NaF), MI Paste™-(CPP-ACP) and the self-assembling peptide 'P' (Ace-QQRFEWEFEQQ-NH) contained in Curodont™ Repair, have on microtensile bond strength-(µTBS) of two different adhesive systems (Adper™ Single Bond-(SB) or Clearfil™ SE Bond (CSE)) and wettability of demineralized dentin slices after remineralising agents were applied. The highest µTBS were found for the demineralized dentin-(DD) treated with CPP-ACP; both adhesives systems (p < 0.05) did not significantly difference from P treatment associated with SB, and also presented higher values than sound dentin-(SD/SB) (p < 0.01). DD treated with P associated with CSE did not differ from DD/CSE (p > 0.05). The NaF treatment associated with CSE recovered the bond strength values of SD/CSE and associated with CSE demonstrated lower µTBS than other groups, although significantly higher than DD (p < 0.05). P and CPP-ACP increased significantly the wettability of demineralized dentin (p < 0.05); etching acid improved wettability for all groups (p < 0.05), whilst NaF did not affect the wettability of demineralized dentin (p > 0.05). Morphological analysis of the dentin surface and dentin-resin interface revealed unique features of the applied remineralizing agent. The results indicated that self-assembling peptide P associated with SB and CPP-ACP associated with SB or CSE significantly enhanced the bond strength to demineralized dentin (p < 0.05). We conclude that by modifying the dentine surface and restoring conditions found on sound dentin, this can enhance the interfacial bonding.

The major goal in restorative dentistry is to develop a true regenerative approach that fully recovers hydroxyapatite crystals within the caries lesion. Recently, a rationally designed self-assembling peptide P11-4 (Ace-QQRFEWEFEQQ-NH2) has been developed to enhance remineralization on initial caries lesions, yet its applicability on dentin tissues remains unclear. Thus, the present study investigated the interaction of P11-4 with the organic dentin components as well as the effect of P11-4 on the proteolytic activity, mechanical properties of the bonding interface, and nanoleakage evaluation to artificial caries-affected dentin. Surface plasmon resonance and atomic force microscopy indicated that P11-4 binds to collagen type I fibers, increasing their width from 214 ± 4 nm to 308 ± 5 nm ( P < 0.0001). P11-4 also increased the resistance of collagen type I fibers against the proteolytic activity of collagenases. The immediate treatment of artificial caries-affected dentin with P11-4 enhanced the microtensile bonding strength of the bonding interface ( P < 0.0001), reaching values close to sound dentin and decreasing the proteolytic activity at the hybrid layer; however, such effects decreased after 6 mo of water storage ( P < 0.05). In conclusion, P11-4 interacts with collagen type I, increasing the resistance of collagen fibers to proteolysis, and improves stability of the hybrid layer formed by artificial caries-affected dentin.

Objective: The present study aimed to verify the influence of training intensity in the aquatic environment on pain, disability, physical capacity, and quality of life in patients with chronic low back pain. Design/Setting: A randomized clinical trial. Subjects: Twenty-two patients with chronic low back pain of both sexes (13 women and 9 men) participated in the study. Material and method: One group performed deep-water walking/running training at moderate intensity (MIT) and a second group performed deep-water walking/running training at high intensity (HIT). Pain, disability, peak oxygen uptake (VO2peak), and quality of life were assessed before and after an intervention. Results: Decreases in pain and disability were observed within both groups, without differences in these parameters between training groups. VO2peak did not change in either group after the training intervention. The results of the HIT group showed more significant improvements in quality of life than that of the MIT group, highlighting the social domain, psychological domain, and general quality of life. Both groups presented significant improvements in the physical and environmental domains of quality of life. Conclusions: Deep-water aerobic exercise training seems to be effective for improving pain symptoms and reducing the disability of people with chronic low back pain. These improvements seem to be independent of the intensity at which the training is performed. In addition, improving pain and disability does not directly reflect all areas of quality of life. In this case, the group that performed the intervention at high intensity achieved more significant improvements in quality of life.

O ambiente escolar tem grande influência sobre a saúde dos jovens, tornando-se um local propício para o desenvolvimento, o apoio e a promoção de programas que conduzam saúde, em especial a saúde bucal, tornando-se o local mais indicado para construção desses hábitos saudáveis, quando inseridos em um programa cotidiano-didático. O estudo teve como objetivo realizar uma revisão integrativa da literatura sobre educação em saúde bucal para escolas. O tema abordado baseou-se em evidências bibliográficas encontradas nas bases de dados Medline e Lilacs, utilizando as seguintes palavras-chave: escola, saúde bucal, educação em saúde e odontologia, no período de 2011 a 2017. Com a participação de dois revisores, foram inclusos estudos publicados em inglês, espanhol e português que apresentassem seus textos publicados na íntegra com o rigor metodológico pré-estabelecido. Foram excluídas monografias, dissertações e teses, bem como estudos em que o resumo não condizia com os objetivos do estudo. Observa-se que a escola se constitui como local privilegiado para ações de promoção de saúde, em virtude do seu potencial para atividades educativas, que irá estimular conhecimento crítico, autonomia, desenvolvimento de habilidades referentes a atitudes mais saudáveis, controle das condições de saúde e qualidade de vida. A compreensão das necessidades de crianças e adolescentes é de suma importância para que os profissionais de saúde e educação se esforcem, no intuito de influenciar positivamente essa população, e atuem junto a eles como multiplicadores de saúde.