Latar Belakang Komplikasi yang dapat terjadi pada pasien Diabetes Mellitus (DM) dapat ditangani dengan melakukan pengendalian DM yaitu manajemen perawatan diri DM. Namun sebagian besar pasien DM tipe 2 memiliki skor perawatan diri yang rendah. Banyak faktor yang mempengaruhi kemampuan pasien DM dalam melakukan perawatan diri salah satunya adalah usia pasien. Objektif. Tujuan penelitian ini adalah untuk mengetahui hubungan umur dan perawatan diri pada pasien Diabetes Mellitus tipe 2. Metode. Populasi penelitian adalah 166 penderita DM tipe 2 dalam 1 tahun terakhir di Puskesmas Kasihan II Bantul. Sampel dalam penelitian ini adalah 2 pasien DM di Puskesmas Kasihan II Bantul dan pengambilan sampel menggunakan non probability sampling dengan quota sampling dan 66 responden sebagai sampel. Pengambilan data dilakukan dengan metode Summary of Diabetes Self-Care Activities (SDSCA) .Resuls. Mayoritas usia responden pada akhir usia lanjut sebanyak 33 orang (52,5%) dan sebagian besar responden memiliki kategori cukup perawatan diri sebagai sebanyak 24 responden (38,1%). Berdasarkan analisis data menggunakan uji korelasi Kendall Tau-b diperoleh r = 0,19, p = 0,067, (p> 0,05). Kesimpulan. Tidak ada hubungan perawatan diri dan usia pada pasien DM tipe 2. Kata Kunci: Usia, Perawatan Diri, Diabetes Mellitus Tipe 2

Pendahuluan: Angka kejadian Gout Arthritis pada lanjut usia dari tahun ke tahun semakin meningkat. Ada banyak faktor yang mempengaruhi kualitas hidup lansia penderita Gout Arthritis. Faktor-faktor tersebut terdiri dari faktor demografi, faktor klinis dan psikologis. Usia dan jenis kelamin merupakan dua faktor demografi yang penting dalam menentukan kualitas hidup lansia dengan penyakit kronis.Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan faktor demografi yaitu usia dan jenis kelamin dengan kualitas hidup lansia dengan Gout Arthritis.Metode: Metode penelitian merupakan penelitian deskriptif analitik korelasional dengan pendekatan waktu cross sectional dengan jumlah sampel 27 lanjut usia di dusun X Sonopakis Kidul Kasihan Bantul. Instrumen kualitas hidup dalam penelitian ini adalah The Short Form-36 (SF-36). Faktor demografi yang meliputi usia, jenis kelamin diukur menggunakan angket dan kartu identitas responden. Korelasi variabel diolah menggunakan Spearman rank.Hasil: Hasil analisis data antara usia dengan kualitas hidup lansia didapatkan nilai p>0,05.Kesimpulan: Kesimpulannya tidak ada hubungan usia dan jenis kelamin dengan kualitas hidup lansia dengan Gout Arthritis di dusun X Sonopakis Kidul Kasihan Bantul.Kata Kunci: usia, jenis kelamin, kualitas hidup, gout arthritis

The pandemic era impacted the decline in learning outcomes and the character of Islamic Kemuhammadiyahan, which was the hallmark of the UNISA Nursing Study program. Knowledge transfer and character-building experience many problems with online lecture meetings. This study aimed to determine the effectiveness of anatomy learning media innovation based on integrating Islamic values into the learning outcomes of anatomy and the formation of Islamic character. The research design used a mixed method: explanatory sequential strategies, starting with a quantitative approach and then a qualitative approach to obtain comprehensive results. The sample used is 227 students. The instrument in this research is the innovation of reproductive anatomy learning media that integrates Islamic values, questionnaires, and interview sheets. The results showed that the provision of pre-posttest material using various learning media improved student learning outcomes and Islamic character (p < 0.05). However, there was no significant difference between learning outcomes and student characteristics when compared between various learning media (p > 0.05). There are 12 themes: obedience to God, brave and confident, rational, critical, creativity and innovation ability, trustworthiness, love of science, working hard and persevering, thinking positively, anticipatory, dynamic, and productive. Learning innovations that integrate Islamic values must be developed to achieve students' hard and soft skills.

The decline of estrogen level causes various skin changes including amount of fibroblast, the thickness of epidermis and dermis. Physical exercise is believed can increase the estrogen level and give benefit impacts on skin. It mechanism is often associated with the increase of extragonadal aromatization and estrogen serum, the activation of insulinlike growth factor (IGF), and the expression of estrogen receptor (ER). This study was conducted to investigate the effect of physical exercise in ovariectomized rat on the amount of fibroblast, the thickness of epidermis and dermis, the levels of ER β in skin and serum estrogen. Eight female Sprague Dawley rats aged 3 months were used in this study. Rats were divided into two groups i.e. Group 1 consisted of ovariectomized rats without physical exercise and Group 2 consisted of ovariectomized rats and given measurable and regular physical exercise. Rats ran on treadmill with the speed 18 m/ min, the tilt of 5%, duration for 60 min/experiment/day, 5 times a week for 12 weeks. The amount of fibroblast, the thickness of epidermis and dermis, the levels of ERβ in skin and serum estrogen were measured after physical exercise. The result showed that there was a significant difference amount of fibroblast between group 1 and group 2 (p<0.05). However, no significant difference the levels of serum estrogen, ERβ, and the thickness of epidermis and dermis between Group 1 and Group 2 (p>0.05). There was a significant positive correlation between the level of serum estrogen and the thickness of epidermis (p<0.05), and negative correlation between the serum estrogen level and the level of ERβ (p<0.05), and negative significant correlation between the level of ERβ and the thickness of epidermis (p<0.05). In conclusion, the amount of dermal fibroblast of ovariectomized rats increase after underwent measurable and regular exercise. There is correlation between the serum estrogen level and the thickness of epidermis as well as ERβ. ABSTRAK Penurunan kadar estrogen dapat menyebabkan perubahan kulit termasuk jumlah fibroblast, ketebalan epidermis dan dermis. Latihan fisik dapat meningkatkan kadar estrogen dan berdampak positif pada kulit. Mekanismenya berhubungan dengan peningkatan aromatisasi ekstragonadal, peningkatan estrogen serum, aktivasi insulinlike growth factor (IGF), serta ekspresi reseptor estrogen (RE). Penelitian ini bertujuan mengkaji pengaruh latihan fisik pada tikus yang dilakukan ovariektomi terhadap jumlah fibroblast, ketebalan epidermis dan dermis, kadar REβ kulit, dan kadar estrogen serum.

This research aims to study factors related to the eventunintended pregnancy adolescent. The analysis used is the chi squaretest. Results of research on the variable level of knowledge about theunintended pregnancy in the case group and 46.7% less category 66.7%of control group both categories. In variable teenage promiscuity themajority of the cases 86.7% less category, 40% of the control groupboth categories. In variable parenting parents, the majority of the cases66.7% less category, 73.3% of the control group both categories. Inthe variable of mass media, the majority of the cases 14% less diversecategories, 33.3% of control group is very diverse categories. There isa relationship between the level of knowledge, relationships teens,parenting parents, and the media with a value of ñ value (0.000) <á(0.05).