Background and Aims:
There has been a lot of confusion in management of apparently healthy individuals whose post prandial plasma glucose levels were lower than fasting levels. It has been observed that many clinicians do send for repeat tests to rule out analytical error since there is common knowledge that post prandial glucose should be higher than fasting glucose level. Blood glucose level is regulated by a fully integrated mechanism with complex interplay of hormones and enzymes on metabolic pathways. Increase or decrease of thyroid hormones can break this equilibrium leading to alterations of carbohydrate metabolism. The objective for this study was to look for subclinical hypothyroidism (SCH) and insulin resistance (IR) in Idiopathic Post prandial glucose lowering and the correlation between thyroid stimulating hormone (TSH) with IR in them.
Methods:
A cross-sectional study with subgroup analysis, 34 cases and 34 controls. Cases comprises of otherwise healthy individuals whose post prandial glucose is lower than fasting glucose and controls as those healthy individual whose post prandial glucose is higher than fasting. Thyroid hormones and insulin were measured in fasting serum samples. Homeostasis model assessment for IR was calculated as per formula.
Results:
Among the 34 cases with idiopathic post prandial glucose lowering, 76% (
n
= 26) had subclinical hypothyroidism and 61% (
n
= 21) had insulin resistance. A positive correlation (r = 0.55) was observed between Thyroid-Stimulating hormone (TSH) and Index of insulin resistance and homeostatic model assessment (HOMA-IR) and was statistically significant with
P
< 0.1.
Conclusions:
The study highlights the importance of evaluating glycoregulatory hormones like thyroid hormones and insulin in cases with idiopathic post prandial glucose lowering for early diagnosis and prevention of overt clinical diseases like Hypothyroidism and Diabetes Mellitus.
Background: Prolonged training as in trained athletes results in the overall increase in muscular mass, metabolic power, and strength which also includes respiratory muscles. Enhancement of the respiratory muscle mass and strength can in turn result in increased respiratory efficiency which will be reflected in the increased lung function values. Aims and Objectives: The aim of this study was to assess the lung function of rowers and runners and to compare the lung function values of athletes in the two sports disciplines. Materials and Methods: This is an observational comparative study conducted on 41 trained athletes consisting of 17 rowers and 24 runners who were selected on the basis of consecutive random sampling method. The participants were asked to come to the department where anthropometric data and cardiovascular variables were recorded which was followed by the recording of lung function values using MEDSPIROR a computerized pneumotachometer. Results: Runners recorded higher lung function values than rowers. Forced vital capacity for runners was 3.36 ± 0.402, rowers was 2.22 ± 0.28, and P value was 0.0001. Forced expiratory volume 1 for runners was 3.18 ± 0.29 and for rowers was 2.005 ± 0.28 with a P value of 0.0001. Maximum voluntary ventilation for runners was 151.58 ± 21.24, and for rowers, it was 119.80 ± 22.93 with a P value of 0.0001. Peak expiratory flow rate value for runners was 9.67 ± 2.71, and for rowers, it was 5.69 ± 1.65 with a P value of 0.0001. Conclusion: The study shows a significant difference between the rowers and runners in their lung function. Runners have a higher lung function values than rowers. Running is therefore a better sports discipline for the enhancement of respiratory efficiency than rowing.
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