The purpose of the present study was to develop and design pectin and polyvinyl pyrrolidone (PVP) blended hydrogel membranes (PEVP), with different pectin: PVP ratios (1:0.2, 1:0.4, 1:0.6, 1:0.8 and 1:1 w/w), which were prepared by using a conventional solution casting technique. An attempt has been made to characterize the hydrogel membranes by various instrumental techniques like, FTIR (Fourier transform infrared) spectroscopy, X-ray diffraction (XRD), Differential scanning calorimetry (DSC), tensile strength test and scanning electron microscopy (SEM). The release patterns of the drug (salicylic acid) from the hydrogel membrane were done in three different release mediums (pH 1.4, pH 7.4 and distilled water) and samples were analyzed spectrophotometrically at 294 nm wavelength on a UV Vis spectrophotometer. MTT assay was done to ensure cytocompatibility of the pectin/PVP hydrogel membranes using B16 melanoma cells. FTIR spectroscopy indicated the presence of secondary amide (I) absorption bands. The XRD study shows decrease in crystallinity of the hydrogel membranes with increase in PVP ratio. DSC study shows an increase in T(g) of pectin after blending with PVP. It was found that tensile strength increases with increasing PVP ratios in the hydrogel membranes. The prepared hydrogel membranes were found to be biocompatible with B16 melanoma cells.

In the current studies attempts were made to prepare hydrogels by chemical modification of pectin with ethanolamine (EA) in different proportions. Chemically modified pectin products were crosslinked with glutaraldehyde reagent for preparing hydrogels. The hydrogels were characterized by Fourier transform infrared spectroscopy (FTIR), organic elemental analysis, X-ray diffraction studies (XRD), swelling studies, biocompatibility and hemocompatibility studies. Mechanical properties of the prepared hydrogels were evaluated by tensile test. The hydrogels were loaded with salicylic acid (used as a model drug) and drug release studies were done in a modified Franz's diffusion cell. FTIR spectroscopy indicated the presence of primary and secondary amide absorption bands. XRD studies indicated increase in crystallinity in the hydrogels as compared to unmodified pectin. The degree of amidation (DA) and molar and mass reaction yields (YM and YN) was calculated based on the results of organic elemental analysis. The hydrogels showed good water holding properties and were found to be compatible with B-16 melanoma cells & human blood.

This work reports the development and characterization of chitosan/ phosphomolybdic acid-based composite membranes. The prepared composite membranes were characterized by Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), differential scanning calorimetry (DSC), tensile strength test, and thermogravimetric analysis (TGA). FTIR spectroscopy indicated the proper molecular interactions between chitosan and PMA. XRD spectroscopy indicated the semi crystalline nature of the composite membranes. DSC study showed the presence of single glass transition temperature (T g ) at 156 C in the 20% PMA-doped membrane, which indicates the miscible nature of chitosan and PMA blend. TGA study indicates increase in thermal stability of the composite membranes as compared to pure chitosan. Mechanical properties of the composite membranes were found to be enhanced significantly.

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This work reports the development and characterization of chitosan/Phosphomolybdic acid (PMA) based composite membranes. The prepared composite membranes were characterized by FTIR (Fourier transform infrared) spectroscopy, X ray diffraction (XRD), differential scanning calorimetry (DSC), tensile strength test, and thermogravimetric analysis (TGA). FTIR spectroscopy indicated the proper molecular interactions between chitosan and PMA. XRD spectroscopy indicated the semi crystalline nature of the composite membranes. DSC study showed the presence of single glass transition temperature (Tg) at 156°C in the 20% PMA doped membrane, which indicates the miscible nature of chitosan and PMA blend. TGA study indicates increase in thermal stability of the composite membranes as compared to pure chitosan. Mechanical properties of the