Birds on a commercial turkey Farm were treated with fenbendazole on two separate occasions. For each treatment, fenbendazole was administered in the feed for 3 days at 30 mg/kg. Mean Ascaridia dissimilis total counts in randomly selected birds were 14.4 and 33.0 prior to the first and second treatments, respectively, whilst post-treatment counts averaged only 0.1 and 0.3, respectively. Anthelmintic effectiveness as demonstrated by both treatments was >99.0%. No untoward effects were noted with either fenbendazole treatment. After fenbendazole withdrawal, routine treatments with piperazine dihydrochloride were commenced with no apparent anthelmintic effectiveness. Mean total nematode burdens rose to 153.9 with a high individual count of 451. The potential for severe ascaridiasis when effective anthelmintic intervention is precluded was demonstrated.

Five experiments were conducted to test the anticoccidial efficacy of salinomycin (AHR-3096C, A. H. Robins) at 66 ppm and its compatibility with roxarsone (50 ppm) under floor pen conditions Monensin (100, 121 ppm), lasalocid (75, 125 ppm), and shuttle programs of salinomycin-monensin (66/100 ppm) or monensin-salinomycin (100/66 ppm) were included for comparison. Coccidiosis exposure was provided by using the infected seeder bird technique. Salinomycin reduced the lesion scores significantly and improved the body weight and feed conversion in all the trials as compared to unmedicated groups. All three ionophores effectively reduced the lesion scores. Birds treated with salinomycin-monensin shuttle programs had lesion scores, body weight, and feed conversion that were not significantly different from the salinomycin treated birds, suggesting that this shuttle program could be used satisfactorily for control of coccidiosis. Lesion scores, body weight, and feed conversion data of the 4th and 5th trials suggested that the anticoccidial activity of salinomycin and roxarsone are additive. There was evidence of compensatory growth after withdrawal of salinomycin and monensin but not with lasalocid.