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Physiological interactions of n-saturated fatty acids, trans-2-unsaturated fatty acids and their methyl and ethyl esters with pre-imaginal stages of Aedes aegypti (L.) have been described. Differences in the response of the larvae and pupae to the same chemical and also the specific interactions of some chemicals synchronized with a short period during the development of a single stage have been emphasized. Investigations of a homologous series of fatty acids and their derivatives indicate that earlier statements to the effect that their toxicity increases as the series is ascended, and that maximum toxicity is reached in the vicinity of capric and lauric acids, should not be accepted without modifications.

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