The release of radiolabeled immunoglobulins from distal end of blocked rat carotid artery was studied in vivo. The elimination half-time was 8-9 min for a 4-5-cm long segment of blocked artery and 16-24 min for a 7-8-cm long segment. Surprisingly high late of convection in completely blocked arteries under conditions of pulsatile pressure has been demonstrated.
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