No abstract

Koro Benguk (Mucuna pruriens D.C.) is a plant that produces medicinal ingredients containing secondary metabolites, one of which is L-DOPA. This compound can be used to treat nervous disorders, treat snake venom, increase body weight and muscle strength, and as an anthelmintic in humans. This study aims to analyze the Benguk Koro Bean (Mucuna pruriens D.C.) In Silico and detect the presence of L-DOPA compounds in the Benguk Koro Bean (Mucuna pruriens D.C.) species using UV-VIS Spectrometry. The methods used are the description method and the data processed descriptively qualitatively. The results showed that in In Silico analysis it was found that the Benguk Koro Bean (Mucuna pruriens D.C.) species in the seeds and leaves contained L-DOPA compounds and had a C9H11NO4 molecular structure, while for the detection of L-DOPA compounds using UV-VIS spectrometry it was detected that Koro Benguk Bean (Mucuna pruriens D.C.) contains L-DOPA with a wavelength of 462 nm with absorbance in seeds and leaves of 2,210 and 1,171, respectively. The conclusion of this study is that with 20 grams of koro benguk seeds it produces 1.105 ppm, while for 2 grams of koro benguk leaves it produces 0.5855 ppm.

Pandemi Coronavirus disease atau yang biasa disebut COVID-19 menimbulkan dampak di berbagai sektor kehidupan masyarakat. Perlu upaya serius untuk meningkatkan ketahanan tubuh dengan memanfaatkan ramuan herbal yang banyak kita jumpai di kebun tanaman obat keluarga. Program edukasi kader penggerak PKK tentang ramuan herbal pencegahan COVID-19 ini dilaksanakan di Kota Batu propinsi Jawa Timur. Penyampaian program melalui ceramah, pelatihan dan FGD UMKM Griya Jamu Siti Ara Kota Batu pada Desember 2021. Edukasi interaktif dengan memberikan materi berupa ceramah tentang khasiat jamu/herbal dan pelatihan keterampilan meracik jamu/herbal.  Analisis uji korelasi Kendall’s tau-b menunjukkan adanya hubungan karakteristik sosioekonomi dan pendidikan dengan persepsi COVID-19. Uji korelasi Pearson menunjukkan tidak terdapat hubungan paparan COVID-19 dengan persepsi peserta engan COVID-19. Danlagi, uji Chi-Square menunjukkan tidak terdapat hubungan karakteristik sosioekonomi dan pendidikan peserta dengan perilaku konsumsi jamu atau herbal. Sejumlah 35 peserta terlibat aktif selama kegiatan. Domisili mereka meliputi seluruh wilayah Kota Batu, Malang Jawa Timur. Dapat disimpulkan bahwa program edukasi ramuan herbal pada penggerak kader PKK mampu meningkatkan pengetahuan dan pemahaman masyarakat dalam pemanfaatan jamu/herbal untuk mencegah COVID-19 kepada seluruh lapisan masyarakat.

No abstract

In the current work, iron nanoparticles (Fe-NPs) were prepared from extracts of Ruellia tuberosa L. extracted with ethanol and water, and their antibacterial activities toward pathogenic bacteria (S. aureus and E. coli) were investigated. The morphologies, structures, sizes and distribution of atom on the surface of Fe-NPs were checked by SEM-EDS, UV-Vis and FTIR spectroscopy. The pH conditions (3, 5, 7, and 9) were chosen as experimental factors for the preparation of Fe-NPs. Formation of results in mostly spherical shapes with particle size found within the range 15-50 nm, and the smallest particle size was obtained from pH 9. UV-Vis spectra confirmed that the formation of Fe-NPs emerged in the UV region around 275 nm. FTIR spectra showed the presence of polyphenolic compounds from extracts of R. tuberosa L, that decreasing aggregations of Fe-NPs and act as bioreductors. As Fe(II) reduced to Fe(0), oxidation of O, OH, and CHO, COOH occurred. The optimal condition for antibacterial activities was at pH 3, resulted in the 16.70 and 13.40 mm of inhibition zones, for S. aureus and E. coli, respectively.