Mycochemical composition, calorific value, the antioxidant activity of Pleurotus tuber-regium was analyzed and impact of P. tuber-regium extract on rat model especially glycemic, vitamins and blood parameters were explored to validate its medicinal importance. Mycochemical screening showed the presence of biochemicals such as phenols, flavonoids, proteins, carbohydrates etc. The extract showed good antioxidant activity (33.62% total antioxidant activity equivalent to 21.30 µg ascorbic acid). The extract showed dose -dependent hypoglycaemic activity by significant decreased average blood glucose level at high dose (100.62 ± 1.04mg/dL) compare to control (124.40 ± 1.45 mg/dL), haematinic activity by elevation of hemoglobin (14.75 ± 0.24 g/dL) at a high dose of extract compared to control (11.66 ± 0.21 g/dL). P. tuber-regium extract elevated vitamin B12 of rats at high dose of extract (449.60 ± 3.12 pg/mL) compared to control (420.00 ± 2.86pg/mL). P. tuber-regium extract showed a positive response to hypoglycemic, haematinic, and vitamin level of the body and posses high calorific value. Hence P. tuber-regium can be used as good fodder, medicinal and nutritional supplement.

A study was carried out to screen lovastatin producing ability in Higher Basidiomycetous Fungi isolates from India. For this an extended screening was performed for lovastatin production in Potato Dextrose medium (solid and liquid medium), among a total of 40 basidiomycetous isolates which were obtained from NTCC, Forest Pathology Discipline, Forest Protection Division, Dehradun, Uttarakhand, India). Lovastatin production was evaluated by the disc diffusion method and agar well diffusion method. During the bioassay experiment with Neurospora crassa 159 only six isolates were found to be lovastatin producers viz.,

Mushrooms are saprophytic fungal organisms grown on dead organic wastes derived from both plants and animals. They extracted the available nutrients from the different sources by decomposition process. Generally, edible mushrooms have high nutritive values like rich of proteins, vitamins and minerals, low level of carbohydrates and lipids. In the present study Oyster mushroom (Pleurotus ostreatus) were cultivated using various substrates news paper waste, coir waste, ground nut shell coat waste and paddy straw wastes under aseptic condition. The nutritional value of all the harvested mushroom basidiocarps from the various substrates have been analysed by determining the moisture, total ash (biomass), protein, fat, lipid and carbohydrates. Among this higher protein content was observed in both news paper wastes (51.93 b ± 3.066 % and ground nut shell (43.06 ab ±6.025 %) wastes based mushrooms. (Pleurotus ostreatus.) Thus edible mushrooms can be cultivated using biodegradable wastes from various sources. This commercial technology could be applied in small scale industry for production of Pleurotus mushrooms which was nutritionally efficient for our health at low cost.