Ulcerative dermatitis of the nasal planum or haired skin of the face, associated with intranuclear inclusion bodies compatible with herpesvirus, was identified in nine cats. Clinically, lesions were ulcerative and crusted, and often persistent. A tenth cat had focal proliferative ulcerative stomatitis, also associated with intranuclear inclusion bodies. Microscopically, there was necrosis and ulceration associated with prominent eosinophilic inflammation. Intranuclear inclusion bodies were noted in all cases, within the surface or adnexal epithelium. Ultrastructural examination of skin from two cats revealed virions morphologically compatible with a herpesvirus. Polymerase chain reaction (PCR) specific for feline herpesvirus 1 on DNA extracted from fresh‐frozen or formalin‐fixed paraffin‐embedded biopsy samples and/or consensus primer PCR with DNA sequencing performed on DNA extracted from formalin‐fixed paraffin‐embedded biopsy samples from seven cats revealed that the virus was indistinguishable from feline herpesvirus 1. PCR was negative in one of eight cats tested.
The histological features of a follicular dysplasia with pigmentary changes is reported in two adult cows, one a black Brangus-cross and the other a black Angus. Adult onset of diuse alopecia was present in both cows. Skin biopsies exhibited follicular distortion and atrophy, with melanin clumping in follicular epithelium, hair bulb matrix cells, hair shafts, and infundibular keratin. Both animals were clinically normal apart from the alopecia. This report con®rms and expands on the infrequently reported syndrome of follicular dysplasia in cattle.
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