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RESUMO: Extratos etanólicos deQualea grandifl ora e Copernicia prunifera e extrato hexânico de Dipteryx lacunifera foram avaliados quanto a atividade antibacteriana, utilizando ensaios de difusão a partir de orifício e concentração inibitória mínima (CIM), frente a cepas Gram positivas e Gram-negativas, incluindo espécies multidroga resistentes. O extrato de Q. grandifl ora apresentou atividade moderada para as cepas de Staphylococcus epidermidis (CIM = 500 g/ mL) e atividade fraca sobre as demais bactérias Gram-positivas testadas e inativo sobre bactérias Gram-negativas. Os resultados obtidos com S. epidermidis apesar de moderados são importantes, uma vez que este microorganismo é o principal causador de bacteremias e sepse associada com dispositivos médicos implantados. -Tocoferol e a mistura de sitosterol e estigmasterol foram isolados do extrato etanólico de raiz de C. prunifera e as estruturas destes compostos foram identifi cadas com base na análise dos dados espectrais de RMN e comparação com a literatura. Unitermos: Qualea grandifl ora, Copernicia prunifera, Dipteryx lacunifera, atividade antibacteriana, isoprenóides.ABSTRACT: "Antibacterial activity of useful plants and chemical constituents of the roots of Copernicia prunifera". Ethanol extracts of Qualea grandifl ora and Copernicia prunifera and hexane extract of Dipteryx lacunifera were evaluated by diffusion in agar and minimum inhibitory concentration (MIC) against Gram-positive and Gram-negative bacteria including multiresistant drug strains. The extract of Q. grandifl ora presented moderate activity for Staphylococcus epidermidis (MIC = 500 g/mL) and weak activity against other Gram-positive strains and inactive for Gram-negative species. The results obtained for S. epidermidis despite being moderate are important because this pathogen is often recovered from bacteremia and sepsis from infections of implanted devices. -Tocopherol and the mixture of sitosterol and stigmasterol were isolated from the ethanol extract of the roots of C. prunifera. The structures of these compounds were identifi ed by NMR spectroscopy and comparison with literature data.

α-PHE has an antinociceptive effect and it possibly involves the glutamatergic, opioid, nitrergic, cholinergic and adrenergic systems.

These results indicate the antinociceptive effect of Lecythis pisonis leaves and suggest that this effect may be related to opioid pathway, K+ATP channels, and L-arginine-nitric oxide modulation. Furthermore, these data support the ethnomedical use of this plant.