The World Health Organization is still revising the epidemiology of multi-system inflammatory syndrome in children (MIS-C) and the preliminary case definition, although there is a dearth of robust evidence regarding the clinical presentations, severity, and outcomes. Researchers, epidemiologists, and clinicians are struggling to characterize and describe the disease phenomenon while taking care of the diseased persons at the forefronts. This report tackles the first case of a 13-year-old Saudi female with the MIS-C mimicking Kawasaki disease. Her main manifestations were fever, gastrointestinal symptoms, evidence of organ failure with an increase in inflammatory markers, and a history of coronavirus disease (COVID-19) infection. She had glucose-6-phosphate dehydrogenase (G6PD) deficiency and no significant previous history of any disease. She presented with signs of acute illness: high-grade fever (39.6°C) for five days accompanied by sore throat, malaise, reduced oral intake, abdominal pain, diarrhea, skin rash, bilateral non-suppurative conjunctivitis, and erythematous, cracked lips. Eventually, she died despite aggressive management based on the Centers for Disease Control and Prevention and the Saudi Ministry of Health guidelines for COVID-19 management. Based on this case, we suggest that pediatricians need to be aware of such atypical presentations and early referral to tertiary care is imperative for further early diagnosis and management. MIS-C is a rare yet severe and highly critical complication of COVID-19 infection in pediatrics, leading to serious and life-threatening illnesses. Knowledge about the wide spectrum of presenting signs and symptoms and disease severity, including early detection and treatment, is pivotal to prevent a tragic outcome.

Objectives This study investigated the quality of life (QoL) of nursing internship students (NISs) and the predictive variables for the QoL of NISs during the COVID-19 pandemic. The correlates of QoL of NISs with their gender, age, prior nursing experience, and grade point average (GPA) from the previous semester are also assessed. Methods This study used a quantitative cross-sectional design through an electronic survey form for the collection of required data. The 22-item Quality of Life Evaluation Scale (QOLES) was adopted as the survey instrument. A total of 283 NISs from five public universities in KSA completed the survey. Results The students' age, gender, and nursing-related experience prior to their internship were all found to be significantly associated with the overall QOLES score ( p values of 0.001, 0.001, and 0.01, respectively). The NISs GPA was found to be marginally significant ( p = 0.08). A significant difference was identified in the overall QOLES score based on age ( p = 0.02), gender ( p = 0.02), and GPA ( p = <0.001). Finally, as estimated by the regression analysis, only age ( p = 0.002) was found to be a significant predictor of NISs’ QoL. Conclusion In this study, the QoL of Saudi NISs was positively correlated with their age and gender. Male NISs had greater QoL than females, while a high QoL was observed among students with high GPAs before the internship year. Only the age of the NISs was found to be a reliable predictor of QoL.

Nowadays, Nosocomial infection and hospital-acquired infection are a worldwide problem that increases morbidity and mortality among the hospitalized patients and surges an additional cost. Rural nurses have a paramount role in preventing infection and providing high quality of patient care. Aim: This study existed to assess the effectiveness of an in-service education program for improving nurses' performance concerning the application of infection control measures in rural hospitals. Setting: This study was conducted in a selected government rural hospital in Fayoum Governorate, Egypt. Sample: A purposive sample of 100 nurses working in the rural hospital were included. Tools: A structured interview guide was used to assess nurses' level of knowledge, and an observation checklist to assess their performance level before and after program implementation. Results: Nearly half of nurses had correct performance concerning infection control pre-program and improved to around 88.0% post-program implementation. There were statistically significant differences between nurse's total knowledge scales and subscales in pre and post-program. Likewise, there were highly statistically significant differences associated with nurses' correct performance score level pre and post-program. Conclusion: In-service education intervention reported incredible improvement in nurses' knowledge and performance toward infection control measures in the rural hospital. Recommendations: There is a desire for endless training courses for nurses to validate nurses' knowledge, performance regarding utilization of standard safeguards of infection control in the rural hospital. Finally, at the community level, the government has to consider the distribution of continuous education programs to expand all health services and resources in rural areas.

Background: The newborn's mother is the key person who takes care and fulfills the needs of the newborn either physiological or psychological. Therefore, it is essential to apply instructional programs that appreciate mothers to have the correct knowledge, home care practice, and attitude to raise their healthy children. Aim: To evaluate the effect of instructional guidelines on mothers' knowledge and practice regarding their neonatal care. Subjects and Methods: Design: A quasi-experimental research design was used. Setting:The study was conducted in maternal and child health centers at Sohag City (Dar E Salam Abdallah health center). Sample: Α Purposive sample of 150 newborns and their mothers. Tool for data collection: A structured interview questionnaire, which included three parts; (I) demographic characteristics; (II) mothers' knowledge and (III) the reported practice (pre/post) regarding breast feeding, thermal control, skin care, and cord care. Results: The main source of information for mothers was their family. Ther was an improvement of mothers' knowledge regarding all aspects of care of their neonates before and after implementation of instructional guidelines. there was a statistically significant difference in mothers' reported care practices of their neonates before and after implementation of the instructional guidelines regarding breastfeeding, kept warm practice, skin care practice, and cord care practices. Conclusion: Instructional guidelines had а positive effect on mothers' knowledge and reported practice regarding neonatal care. Recommendations: Instructional guidelines regarding neonatal care should be applied for newly mothers during antenatal period.

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